Semaxanib

SEMBL is a potent NF-κB inhibitor. SEMBL can inhibit NF-κB-DNA binding, and also inhibits NF-κB-dependent inflammatory cytokine secretions. SEMBL inhibits cancer cell migration and invasion via decreasing MMP expression. SEMBL can be used for

Biochem/physiol Actions SR-318 is a potent and selective type-II inhibitor that targets p38&#945:/&#946: in an inactive DFG-out conformation with good kinome selectivity (p38&#945:/&#946: IC 50 = 5/39 nM by radiometric kinase assay). SR-318

Biochem/physiol Actions SR-318 is a potent and selective type-II inhibitor that targets p38&#945:/&#946: in an inactive DFG-out conformation with good kinome selectivity (p38&#945:/&#946: IC 50 = 5/39 nM by radiometric kinase assay). SR-318

A very potent inhibitor of sEH (IC₅₀ = 0.5 nM) displays high oral bioavailability for doses ranging from 0.

A very potent inhibitor of sEH (IC₅₀ = 0.5 nM) displays high oral bioavailability for doses ranging from 0.

A very potent inhibitor of sEH (IC₅₀ = 0.5 nM) displays high oral bioavailability for doses ranging from 0.

A very potent inhibitor of sEH (IC₅₀ = 0.5 nM) displays high oral bioavailability for doses ranging from 0.

UNC5293 is a MERTK -selective and potent inhibitor ( K i =190 pM). UNC5293 inhibits MERTK ( IC 50 =0.9 nM) and is more selective over Axl, Tyro3 and Flt3 . UNC5293 exhibits excellent mouse PK properties and is used for bone marrow leukemia

UNC5293 is a MERTK -selective and potent inhibitor ( K i =190 pM). UNC5293 inhibits MERTK ( IC 50 =0.9 nM) and is more selective over Axl, Tyro3 and Flt3 . UNC5293 exhibits excellent mouse PK properties and is used for bone marrow leukemia

altering the lifespan of a eukaryotic organism: anti-cancer:.

A natural monocyclic sesquiterpene that potently inhibits the activation of Epstein-Barr virus by phorbol esters (IC₅₀ = 140 nM) inhibits SHH signaling and induces apoptosis in cancer cell lines.

Harmonized Tariff Code:  9027.90 Risk Phrases: 23/25-33 Toxic by inhalation and if swallowed. Danger of cumulative effects. Safety Phrases: 20/21-28a-45 When using do not eat, d