Antipsychotic spiro compounds

General description This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles.

Biochem/physiol Actions Misfolded proteins accumulate in many neurodegenerative diseases, including huntingtin in Huntington&#8242s disease and alpha-synuclein in Parkinson&#8242s disease. The disease-causing proteins can take various

Application N-Desmethylclozapine has been used as standard to quantify the clozapine plasma levels in treatment-refractory Chinese schizophrenic patients. Biochem/physiol Actions N-Desmethylclozapine serves as an agonist to muscarinic acetylcholine

Application N-Desmethylclozapine has been used as standard to quantify the clozapine plasma levels in treatment-refractory Chinese schizophrenic patients. Biochem/physiol Actions N-Desmethylclozapine serves as an agonist to muscarinic acetylcholine

InformationSB590885 is a potentB-Rafinhibitor withKiof 0.16 nM in a cell-free assay, 11-fold greater selectivity for B-Raf over c-Raf, no inhibition to other human kinases.In vitroSB590885 displays significant selectivity for B-Raf over c-Raf with

SKF83959 is a potent and selective dopamine D 1 -like receptor partial agonist. SKF83959 K i values for rat D 1 , D 5 , D 2 and D 3 receptors are 1.18, 7.56, 920 and 399 nM, respectively. SKF83959 is a potent allosteric modulator of sigma (σ)-1

SKF83959 is a potent and selective dopamine D 1 -like receptor partial agonist. SKF83959 K i values for rat D 1 , D 5 , D 2 and D 3 receptors are 1.18, 7.56, 920 and 399 nM, respectively. SKF83959 is a potent allosteric modulator of sigma (σ)-1

SKF83959 is a potent and selective dopamine D 1 -like receptor partial agonist. SKF83959 K i values for rat D 1 , D 5 , D 2 and D 3 receptors are 1.18, 7.56, 920 and 399 nM, respectively. SKF83959 is a potent allosteric modulator of sigma (σ)-1

SKF83959 is a potent and selective dopamine D 1 -like receptor partial agonist. SKF83959 K i values for rat D 1 , D 5 , D 2 and D 3 receptors are 1.18, 7.56, 920 and 399 nM, respectively. SKF83959 is a potent allosteric modulator of sigma (σ)-1

Spherisorb Amino (NH2) Cartridge, 80Å, 5 µm, 4.6 mm X 50 mm, 1/pk

Sphingosine

Sphingosine