Atevirdine

Biochem/physiol Actions 2&#8242:-C-Methylcytidine is a potent inhibitor of the HCV NS5B RNA polymerase. 2&#8242:-C-Methylcytidine was the first nucleoside NS5B inhibitor that showed clinical efficacy.

Biochem/physiol Actions 2&#8242:-C-Methylcytidine is a potent inhibitor of the HCV NS5B RNA polymerase. 2&#8242:-C-Methylcytidine was the first nucleoside NS5B inhibitor that showed clinical efficacy.

InformationAG-1478 (Tyrphostin AG-1478, NSC 693255) is a selectiveEGFRinhibitor withIC50of 3 nM in cell-free assays, almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR. AG-1478 (Tyrphostin AG-1478) inhibitsencephalomyocarditis virus

Biochem/physiol Actions Originally recognized as a powerful mutagen that preferentially induces AT-to-GC transition in microorganisms, EIDD-1931 (NHC, N4-hydroxycytidine) is an orally available ribonucleoside analog with known anti-viral activity

Biochem/physiol Actions Originally recognized as a powerful mutagen that preferentially induces AT-to-GC transition in microorganisms, EIDD-1931 (NHC, N4-hydroxycytidine) is an orally available ribonucleoside analog with known anti-viral activity

A natural alkaloid mycotoxin that blocks activation of the HIV LTR by TNF-&alpha in HeLa cells (IC₅₀ = 5 &microM) inhibits virus production in OM-10.1 cells (HL-60 promyelocytes infected with HIV-1) treated with TNF-&alpha

A natural alkaloid mycotoxin that blocks activation of the HIV LTR by TNF-&alpha in HeLa cells (IC₅₀ = 5 &microM) inhibits virus production in OM-10.1 cells (HL-60 promyelocytes infected with HIV-1) treated with TNF-&alpha

InformationRemdesivir (GS-5734), a monophosphoramidate prodrug of an adenosine analog, is an investigational broad-spectrumantiviralagent with in vitro activity against multiple RNA viruses, including Ebola and CoV.In vitroGS-5734 exhibits antiviral

InformationTecovirimat Tecovirimat (Arestvyr, SIGA-246, ST-246, TPOXX) is an antiviral that inhibits the egress of orthopoxviruses by targeting viral p37 protein orthologs . Tecovirimat is developed for the treatment of smallpox infection.Targetsp37

InformationTecovirimat Tecovirimat (Arestvyr, SIGA-246, ST-246, TPOXX) is an antiviral that inhibits the egress of orthopoxviruses by targeting viral p37 protein orthologs . Tecovirimat is developed for the treatment of smallpox infection.Targetsp37

InformationTecovirimat Tecovirimat (Arestvyr, SIGA-246, ST-246, TPOXX) is an antiviral that inhibits the egress of orthopoxviruses by targeting viral p37 protein orthologs . Tecovirimat is developed for the treatment of smallpox infection.Targetsp37

TMC647055 (Choline salt) is a potent nonnucleoside NS5B polymerase inhibitor of HCV replication . TMC647055 Choline salt has potent HCV combine activity with an IC 50 value of 82 nM. TMC647055 Choline salt can be used for the research of Hepatitis C