Central nervous system drugs

A potent, orally bioavailable inhibitor of &gamma-secretase that more potently inhibits the cleavage of APP to A&beta40 than signaling through Notch (IC₅₀s = 0.30 and 58 nM, respectively) shows good pharmacokinetics in rats, dogs, and

Potent and selective antagonist for the CB1 receptor (Ki = 0.16-0.

Potent and selective antagonist for the CB1 receptor (Ki = 0.16-0.

Potent and selective antagonist for the CB1 receptor (Ki = 0.16-0.

General description This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate.

Avermectin B1a is a macrocyclic lactone that makes up a large component of the anthelimintic Abamectin used to control parasitic nematodes in livestock. Avermectin B1a also acts as an insecticide and acaricide. The avermectins are used commercially

Avermectin B1a is a macrocyclic lactone that makes up a large component of the anthelimintic Abamectin used to control parasitic nematodes in livestock. Avermectin B1a also acts as an insecticide and acaricide. The avermectins are used commercially

Avermectin B1a is a macrocyclic lactone that makes up a large component of the anthelimintic Abamectin used to control parasitic nematodes in livestock. Avermectin B1a also acts as an insecticide and acaricide. The avermectins are used commercially

Avermectin B1a is a macrocyclic lactone that makes up a large component of the anthelimintic Abamectin used to control parasitic nematodes in livestock. Avermectin B1a also acts as an insecticide and acaricide. The avermectins are used commercially

Avermectin B1a is a macrocyclic lactone that makes up a large component of the anthelimintic Abamectin used to control parasitic nematodes in livestock. Avermectin B1a also acts as an insecticide and acaricide. The avermectins are used commercially

A partial agonist of the GABAA receptor that acts at the benzodiazepine binding site, dose-dependently stimulating GABA currents with a threshold of 0.3-1.

A partial agonist of the GABAA receptor that acts at the benzodiazepine binding site, dose-dependently stimulating GABA currents with a threshold of 0.3-1.