Caffeine/sodium benzoate

Perazine is a human cytochrome P450 isoenzyme 1A2 (CYP1A2) inhibitor. Dixon analysis in human liver microsomes and Supersomes CYP1A2 showed potent inhibition of caffeine 3-N-demethylation and 1-N-demethylation, as well as moderate inhibition of

Perazine-d8 is a deuterated form of Perazine , a human cytochrome P450 isoenzyme 1A2 (CYP1A2) inhibitor. Dixon analysis in human liver microsomes and Supersomes CYP1A2 showed Perazine acts as a potent inhibitor of caffeine 3-N-demethylation and

Perazine-d8 is a deuterated form of Perazine , a human cytochrome P450 isoenzyme 1A2 (CYP1A2) inhibitor. Dixon analysis in human liver microsomes and Supersomes CYP1A2 showed Perazine acts as a potent inhibitor of caffeine 3-N-demethylation and

Biochem/physiol Actions PF-04449613 is a potent and selective cGMP-competitive PDE9A inhibitor (IC 50 = 24 nM: IC 50 &gt:800 nM against other PDE members), displaying more than 1000-fold selectivity over the majority of 79 non-PDE targets

Biochem/physiol Actions PF-04449613 is a potent and selective cGMP-competitive PDE9A inhibitor (IC 50 = 24 nM: IC 50 &gt:800 nM against other PDE members), displaying more than 1000-fold selectivity over the majority of 79 non-PDE targets

S-(+)-Arundic Acid is the S-enantiomer of Arundic Acid. An astrocyte modulating agent, in acute ischemic stroke. A therapeutic agent for the treatment of neurodegenerative diseases including Alzheimer's disease and Parkinson's disease.

A dual antagonist of both OX1R and OX2R (Kis = 0.2 and 3 nM, respectively) that demonstrates good brain penetration when administered intraperitoneally promotes sleep, prevents drug-induced plasticity and drug relapse, and decreases fear and

A dual antagonist of both OX1R and OX2R (Kis = 0.2 and 3 nM, respectively) that demonstrates good brain penetration when administered intraperitoneally promotes sleep, prevents drug-induced plasticity and drug relapse, and decreases fear and

A dual antagonist of both OX1R and OX2R (Kis = 0.2 and 3 nM, respectively) that demonstrates good brain penetration when administered intraperitoneally promotes sleep, prevents drug-induced plasticity and drug relapse, and decreases fear and

Theobromine-d6 is a labeled metabolite of Caffeine.

Biochem/physiol Actions UCSF7447 (ZINC555417447) brain permeable, potent and selective inverse agonist of both human and mouse melatonin MT1 receptor, which decelerates re-entrainment in mouse model of east-bound jetlag. Unexpectedly UCSF7447

Biochem/physiol Actions UCSF7447 (ZINC555417447) brain permeable, potent and selective inverse agonist of both human and mouse melatonin MT1 receptor, which decelerates re-entrainment in mouse model of east-bound jetlag. Unexpectedly UCSF7447