Carisbamate

Specificity GABAA Receptor alpha 5 subunit. The antibody recognizes a protein of ~55 kDa corresponding to GABAA Receptor alpha 5 subunit in lysates from rat hippocampus and thalamus.

General description The antibody detects endogenous level of total GABA A Receptor a3 protein. Immunogen Peptide sequence around aa.

Biochem/physiol Actions Carisbamate is an antiepileptic agent with broad anticonvulsant and neuroprotective activity. It has also been investigated as a possible treatment for alcohol dependence.

CXCR2-IN-2 is a selective, brain penetrant, and orally bioavailable CXCR2 antagonist ( IC 50 =5.2 nM/1 nM in β-arrestin assay/CXCR2 Tango assay, respectively). CXCR2-IN-2 displays ~730-fold selectivity over CXCR1 and &gt:1900-fold selectivity over

CXCR2-IN-2 is a selective, brain penetrant, and orally bioavailable CXCR2 antagonist ( IC 50 =5.2 nM/1 nM in β-arrestin assay/CXCR2 Tango assay, respectively). CXCR2-IN-2 displays ~730-fold selectivity over CXCR1 and &gt:1900-fold selectivity over

CXCR2-IN-2 is a selective, brain penetrant, and orally bioavailable CXCR2 antagonist ( IC 50 =5.2 nM/1 nM in β-arrestin assay/CXCR2 Tango assay, respectively). CXCR2-IN-2 displays ~730-fold selectivity over CXCR1 and &gt:1900-fold selectivity over

CXCR2-IN-2 is a selective, brain penetrant, and orally bioavailable CXCR2 antagonist ( IC 50 =5.2 nM/1 nM in β-arrestin assay/CXCR2 Tango assay, respectively). CXCR2-IN-2 displays ~730-fold selectivity over CXCR1 and &gt:1900-fold selectivity over

CXCR2-IN-2 is a selective, brain penetrant, and orally bioavailable CXCR2 antagonist ( IC 50 =5.2 nM/1 nM in β-arrestin assay/CXCR2 Tango assay, respectively). CXCR2-IN-2 displays ~730-fold selectivity over CXCR1 and &gt:1900-fold selectivity over

CXCR2-IN-2 is a selective, brain penetrant, and orally bioavailable CXCR2 antagonist ( IC 50 =5.2 nM/1 nM in β-arrestin assay/CXCR2 Tango assay, respectively). CXCR2-IN-2 displays ~730-fold selectivity over CXCR1 and &gt:1900-fold selectivity over

Carbenoxolone is a synthetic derivative of the active component of licorice (Glycyrrhiza glabra) and is most well known for its ability to inhibit gap junction connexin channels and 11&szlig-hydroxysteroid dehydrogenase. Carbenoxolone displays a

Carbenoxolone is a synthetic derivative of the active component of licorice (Glycyrrhiza glabra) and is most well known for its ability to inhibit gap junction connexin channels and 11&szlig-hydroxysteroid dehydrogenase. Carbenoxolone displays a

Carbenoxolone is a synthetic derivative of the active component of licorice (Glycyrrhiza glabra) and is most well known for its ability to inhibit gap junction connexin channels and 11&szlig-hydroxysteroid dehydrogenase. Carbenoxolone displays a