Clobenzorex

Pixantrone Dimaleate is a synthetic anthracene-9,10-dione that has anti-tumor activity and is considered a promising immunosuppressant agent for treatment of multiple sclerosis.

Pixantrone Dimaleate is a synthetic anthracene-9,10-dione that has anti-tumor activity and is considered a promising immunosuppressant agent for treatment of multiple sclerosis.

InformationPLX5622 PLX5622 is a highly selective CSF-1R inhibitor (IC50 &lt: 10 nmol/L), showing &gt: 20-fold selectivity over KIT and FLT3.TargetsCSF-1R (Cell-free assay): FLT3 (Cell-free assay): KIT (Cell-free assay): AURKC (Cell-free assay): KDR

InformationPLX5622 PLX5622 is a highly selective CSF-1R inhibitor (IC50 &lt: 10 nmol/L), showing &gt: 20-fold selectivity over KIT and FLT3.TargetsCSF-1R (Cell-free assay): FLT3 (Cell-free assay): KIT (Cell-free assay): AURKC (Cell-free assay): KDR

InformationPLX5622 PLX5622 is a highly selective CSF-1R inhibitor (IC50 &lt: 10 nmol/L), showing &gt: 20-fold selectivity over KIT and FLT3.TargetsCSF-1R (Cell-free assay): FLT3 (Cell-free assay): KIT (Cell-free assay): AURKC (Cell-free assay): KDR

InformationPLX5622 PLX5622 is a highly selective CSF-1R inhibitor (IC50 &lt: 10 nmol/L), showing &gt: 20-fold selectivity over KIT and FLT3.TargetsCSF-1R (Cell-free assay): FLT3 (Cell-free assay): KIT (Cell-free assay): AURKC (Cell-free assay): KDR

InformationPLX5622 PLX5622 is a highly selective CSF-1R inhibitor (IC50 &lt: 10 nmol/L), showing &gt: 20-fold selectivity over KIT and FLT3.TargetsCSF-1R (Cell-free assay): FLT3 (Cell-free assay): KIT (Cell-free assay): AURKC (Cell-free assay): KDR

Application CLIA: 1μg/mlELISA: 1μg/ml.

Application CLIA: 1μg/mlELISA: 1μg/ml.

Application CLIA: 1μg/mlELISA: 1μg/ml.

Application CLIA: 1μg/mlELISA: 1μg/ml.

Purmorphamine, which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo with IC50 of ~ 1.5 μM and also is an inducer of osteoblast differentiation with EC50 of 1 μM.An activator of the hedgehog (Hh) signaling pathway.