Epsom salt or magnesium sulfate

Biochem/physiol Actions ADX-47273 is a brain-penetrating, potent and selective metabotropic glutamate receptor 5 (mGlu5: mGluR5) positive allosteric modulator (PAM) that enhances glutamate-stimulated Ca2+ response in rat cortical astrocytes (EC50

Biochem/physiol Actions ADX-47273 is a brain-penetrating, potent and selective metabotropic glutamate receptor 5 (mGlu5: mGluR5) positive allosteric modulator (PAM) that enhances glutamate-stimulated Ca2+ response in rat cortical astrocytes (EC50

InformationADX47273 (BA 94673139) is a potent and specificmGlu5positive allosteric modulator(PAM) withEC50of 0.17 μM, showing no activity at other mGlu subtypes.In vitroADX47273 causes a concentration-dependent increase in the response to 50 nM

Specificity GABA A receptor alpha4 subunit. The apparent molecular mass of the alpha 4 subunit in rat brain membrane fractions is 64 kDa.

Specificity GABA A receptor alpha6 subunit. The apparent molecular mass of the alpha6 subunit in rat brain membrane fractions is 56-57 kDa.

Specificity Predicted to cross-react with human and mouse based on sequence homology mGluR1 Immunogen peptide corresponding to amino acids 1180-1199 (C-PNVTYASVILRDYKQSSSTL) of rat mGluR1 Application Anti-mGluR1 Antibody detects level of

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be

General description Metabotropic glutamate receptor 5 (mGluR5) is a member of the G-protein coupled receptor family and functions as a receptor for glutamate. mGluR5 activates a phosphatidylinositol-calcium second messenger system and generates a

General description Metabotropic glutamate receptor 5 (mGluR5) is a G-protein mediated glutamate receptor that generates a calcium-activated chloride current. mGluR5 is widely distributed in neuronal cells of the central nervous system.

Specificity This antibody reacts to human and mouse PSD95. It may also react to rat PSD95, as predicted by immunogen homology.

General description PSD95 (postsynaptic density 95) represent a class of anchoring proteins which serve to localize various neuronal ion channels to post-synaptic densities. PSD95 and related proteins contain PDZ domains, which interact with NMDA

CAY10410 is an analog of PGD2/PGJ2 with structural modifications intended to give it PPAR&gamma ligand activity and resistance to metabolism. 15-deoxy-.