Leteprinim potassium

A cell-permeable, reversible and competitive inhibitor of rat brain CaM kinase II (K i = 370 nM). Selectively binds to the CaM binding site of the enzyme and prevents the association of CaM with CaMKII.

A potent, specific, cell-permeable, reversible and ATP-competitive inhibitor of protein kinase A (K i = 56 nM) that is prepared by a chemical modification of K-252a. Does not significantly affect the activities of PKC, PKG, and MLCK.

A potent, specific, cell-permeable, reversible and ATP-competitive inhibitor of protein kinase A (K i = 56 nM) that is prepared by a chemical modification of K-252a. Does not significantly affect the activities of PKC, PKG, and MLCK.

Product Introduction Kynurenic acid is a metabolite of tryptophan in mammals via the kynurenine pathway. Studies have observed that Kynurenic acid acts as a ligand to the GPR35 G protein-coupled receptor. The binding of Kynurenic acid to GPR35 has

Product Introduction Kynurenic acid is a metabolite of tryptophan in mammals via the kynurenine pathway. Studies have observed that Kynurenic acid acts as a ligand to the GPR35 G protein-coupled receptor. The binding of Kynurenic acid to GPR35 has

Product Introduction Kynurenic acid is a metabolite of tryptophan in mammals via the kynurenine pathway. Studies have observed that Kynurenic acid acts as a ligand to the GPR35 G protein-coupled receptor. The binding of Kynurenic acid to GPR35 has

Product Introduction Kynurenic acid is a metabolite of tryptophan in mammals via the kynurenine pathway. Studies have observed that Kynurenic acid acts as a ligand to the GPR35 G protein-coupled receptor. The binding of Kynurenic acid to GPR35 has

Product IntroductionKynurenic acid is a metabolite of tryptophan in mammals via the kynurenine pathway. Studies have observed that Kynurenic acid acts as a ligand to the GPR35 G protein-coupled receptor. The binding of Kynurenic acid to GPR35 has

A metabolite of tryptophan that has pronounced effects on neuronal signaling broadly antagonizes ionotopic glutamate receptors has potent effects at glutamate receptor subunit &zeta-1 (Ki = 5.4 &microM), GPR35 (EC₅₀ = 39 &microM),

A metabolite of tryptophan that has pronounced effects on neuronal signaling broadly antagonizes ionotopic glutamate receptors has potent effects at glutamate receptor subunit &zeta-1 (Ki = 5.4 &microM), GPR35 (EC₅₀ = 39 &microM),

A metabolite of tryptophan that has pronounced effects on neuronal signaling broadly antagonizes ionotopic glutamate receptors has potent effects at glutamate receptor subunit &zeta-1 (Ki = 5.4 &microM), GPR35 (EC₅₀ = 39 &microM),

Leteprinim Potassium Salt is a synthetic purine derivative with neuroprotective effects. A cognitive enhancer that is transported into brain by a nonsaturable influx mechanism and out of the brain by a saturable efflux mechanism.