Mazaticol hydrochloride

(1-Cyclopropyl-1H-imidazol-2-yl)methanol hydrochloride.

(4,5-Dimethyl-1,3-oxazol-2-yl)methanamine.

General description 1&#8242:-Hydroxymidazolam is the metabolite of midazolam. Application 1&#8242:-Hydroxymidazolam (1&#8242:-OHMDZ) can be used for assessing Cyp3a11 enzyme activity as well as for pharmacokinetic (PK) study of midazolam.

General description 1&#8242:-Hydroxymidazolam is the metabolite of midazolam. Application 1&#8242:-Hydroxymidazolam (1&#8242:-OHMDZ) can be used for assessing Cyp3a11 enzyme activity as well as for pharmacokinetic (PK) study of midazolam.

1-(3-Propylisoxazol-5-yl)methanamine hydrochloride.

1-[1-(1H-Imidazol-1-ylmethyl)cyclopropyl]methanamine.

Specificity Specifically recognizes tyrosine hydroxylase phosphorylated at serine 40. Immunogen synthetic phosphorylated peptide corresponding to amino acids residues surrounding the rat TH phosphorylated on serine 40.

Selectively activates hM3Dq (EC₅₀ = 1.7 nM), a DREADD derived from the human muscarinic acetylcholine M3 receptor.

InformationFabomotizole hydrochloride (Fabomotizole, CM346, CM346, Afobazol, Afobazole) exhibits anxiolytic and neuroprotective properties. Fabomotizole hydrochloride is a potentsigma1-receptoragonist with IC50 of 7.1 µM and Ki of 5.9 µM.

Biochem/physiol Actions GMQ/2-Guanidine-4-methylquinazoline is a potent and selective modulator of acid-sensing ion channel (ASIC) that activates ASIC3 channels under neutral pH. GQM blocks acid-induced maximal peak current and alters ASICs pH

Application GW405833 hydrochloride has been used as a lysosomal transient receptor potential mucolipin 1 (TRPML1) specific inhibitor to validate if TRPML1 mediates tau release in neurons and also to verify if it mediates the release of lysosomal

Application GW405833 hydrochloride has been used as a lysosomal transient receptor potential mucolipin 1 (TRPML1) specific inhibitor to validate if TRPML1 mediates tau release in neurons and also to verify if it mediates the release of lysosomal