Methylphenidate

General description Methylation of cytosines located 5&#8242: to guanosine is known to have a profound effect on the expression of several eukaryotic genes (Bird, 1992). In normal cells, methylation occurs predominantly in CG-poor regions, while

General description The CpGenome Rat Methylated Genomic DNA Control is an ideal control or standard in DNA methylation studies. This methylated standard is generated using multiple strand displacement amplification of rat genomic DNA using

CVN424 is an orally active and selective GPR6 inverse agonist with a K i of 9.4 nM and an EC 50 of 38 nM. CVN424 is brain-penetrant and has the potential for Parkinson disease researchIn VitroCVN424 (Compound 6i) has 265 fold and 68 fold

InformationDimethyl Fumarate Dimethyl fumarate (DMF) is the methyl ester of fumaric acid, used to treat people with relapsing forms of multiple sclerosis. Dimethyl fumarate is a nuclear factor (erythroid-derived)-like 2 (Nrf2) pathway activator and

DS-437 is a dual PRMT5/7 inhibitor ( IC 50 s of PRMT5/7=6 μM). DS-437 is selective for PRMT5 and PRMT7 over 29 other human protein-, DNA-, and RNA-methyltransferases. DS-437 is a S-adenosylmethionine (SAM)-competitive inhibitor of PRMT5 . DS-437

Source: Recombinant N-terminal His-tagged protein expressed in Sf21 cells Mr: 53.5 kDa EED is a WD40 repeat-containing protein that forms part of the Polycomb repressive complex 2 (PRC2).

Application GSK-LSD1 has been used as a lysine specific demethylase 1 (LSD1) inhibitor in mice to study sepsis-induced mortality. It has also been used as an inhibitor to study if the effect of phenelzine activation of human immunodeficiency

Application GSK-LSD1 has been used as a lysine specific demethylase 1 (LSD1) inhibitor in mice to study sepsis-induced mortality. It has also been used as an inhibitor to study if the effect of phenelzine activation of human immunodeficiency

Species : Human Assay Principle : Target Name : Cerebral dopamine neurotrophic factor Sensitivity : 1-5h Detection Range :

General description CHL1 (cell adhesion molecule L1 like) gene codes for a cell-adhesion molecule. It belongs to the L1 family of cell adhesion molecules.

Species : Human Assay Principle : Quantitative Target Name : N-Methyl-D-aspartate receptor 1 Sensitivity : 0.1ng/mL Detection Range : 0.25 ng/mL-8 ng/mL

L-Dopa-(phenyl-d 3 ) is an isotopic analogue of 3-(3,4-Dihydroxyphenyl)-L-alanine amino acid. Application L -Dopa-(phenyl-d 3 ) or (3-(3,4-dihydroxyphenyl-2,5,6-d 3 )- L -alanine) can be used as an internal standard for the quantification of