Naltrexone hydrochloride

Biochem/physiol Actions &#946:-Naltrexamine is a potent orally available, long lasting opioid antagonist. &#946:-naltrexamine is obtained from naltrexone.

CP-601932 ((1S,5R)-CP-601927) is a high-affinity partial agonist at α3β4 nAChR ( K i =21 nM: EC 50 =~ 3 μM). CP-601932 has the same high-binding affinity at α4β2 nAChR (K i =21 nM) and an order of magnitude lower affinity for α6 and α7 nAChR

CP-601932 ((1S,5R)-CP-601927) is a high-affinity partial agonist at α3β4 nAChR ( K i =21 nM: EC 50 =~ 3 μM). CP-601932 has the same high-binding affinity at α4β2 nAChR (K i =21 nM) and an order of magnitude lower affinity for α6 and α7 nAChR

CP-601932 ((1S,5R)-CP-601927) is a high-affinity partial agonist at α3β4 nAChR ( K i =21 nM: EC 50 =~ 3 μM). CP-601932 has the same high-binding affinity at α4β2 nAChR (K i =21 nM) and an order of magnitude lower affinity for α6 and α7 nAChR

InformationNaltrexone HCl Naltrexone HCl is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence.In vitroIn vivoNaltrexone (0.32 mg/kg) reduces ethanol-reinforced responding at the concentration

Application Naltrexone hydrochloride has been used: as an opioid antagonist, to analyse its effect on ethanol preference using Caenorhabditis elegans as a model to determine its effectiveness in reducing the preference for substance of abuse

Application Naltrexone hydrochloride has been used: as an opioid antagonist, to analyse its effect on ethanol preference using Caenorhabditis elegans as a model to determine its effectiveness in reducing the preference for substance of abuse

Application Naltrexone hydrochloride has been used: as an opioid antagonist, to analyse its effect on ethanol preference using Caenorhabditis elegans as a model to determine its effectiveness in reducing the preference for substance of abuse