Pyridoxine disulfide or pyrithioxine or pyritinol

Go6976 is a potent PKC inhibitor with IC50 of 7.9 nM, 2.3 nM, and 6.2 nM for PKC (Rat brain), PKCα, and PKCβ1, respectively. Also a potent inhibitor of JAK2 and Flt3.

Go6976 is a potent PKC inhibitor with IC50 of 7.9 nM, 2.3 nM, and 6.2 nM for PKC (Rat brain), PKCα, and PKCβ1, respectively. Also a potent inhibitor of JAK2 and Flt3.

Go6976 is a potent PKC inhibitor with IC50 of 7.9 nM, 2.3 nM, and 6.2 nM for PKC (Rat brain), PKCα, and PKCβ1, respectively. Also a potent inhibitor of JAK2 and Flt3.

InformationH 89 2HCl is a potentPKAinhibitor withKiof 48 nM in a cell-free assay, 10-fold selective for PKA than PKG,500-fold greater selectivity than PKC, MLCK, calmodulin kinase II and casein kinase I/II. H 89 2HCl inducesautophagy.In vitroH89

A cell-permeable protein kinase C (PKC) inhibitor that selectively inhibits PKC &#945 (IC 50 = 43 &#181M) and PKC &#947 (IC 50 = 50 &#181M) over PKC &#948 , &#946 I , and &#946 II isozymes in in vitro assays. Reported to induce apoptosis in

An ELISA kit for the detection of PK2 (Rat). This uses Sandwich ELISA, Double Antibody and has a sensitivity of 0.188ng/ml.

JNJ-42253432 is a CNS-penetrant, high-affinity and orally active P2X7 antagonist, with pK i values of 9.1 and 7.9 for rat and human P2X7 channels, respectively.In VivoWhen dosed in rats, JNJ-42253432 occupied the brain P2X7 channel with an ED 50 of

JNJ-42253432 is a CNS-penetrant, high-affinity and orally active P2X7 antagonist, with pK i values of 9.1 and 7.9 for rat and human P2X7 channels, respectively.In VivoWhen dosed in rats, JNJ-42253432 occupied the brain P2X7 channel with an ED 50 of

Monoclonal Anti-Dystrophin (mouse IgG2b isotype) is derived from the MANDYS8 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. Dystrophin is a structural protein on the inner face of the membrane,

A cell-permeable, blood brain barrier permeable, orally bioavailable, non-toxic benzothiazolone derived compound that acts a potent, reversible and non-covalent inhibitor of protein disulfide isomerase (PDI) reductase activity ( K d = 61.7 nM for

A cell-permeable pyrrolopyrimidinamine compound that acts as a potent, ATP-competitive EIF2AK3/PERK inhibitor (IC 50 = 0.9 nM [ATP] = 10 &#181M), displaying &#8805511-fold selectivity over HRI/EIF2AK1, BRK, PKR/EIF2AK2, and MEKK2 (IC 50 = 460,

PHENYL STYRYL SULFIDE-