Calcium iodide/codeine

An iodinated nonivamide, a potent TRPV1 antagonist with an IC50 value of approximately 10 nM.

A physically smaller, less hydrophobic version of the lidocaine derivative QX314 designed to be more permeable to the TRPV1 ion channel for selective analgesia through TRPV1.

A physically smaller, less hydrophobic version of the lidocaine derivative QX314 designed to be more permeable to the TRPV1 ion channel for selective analgesia through TRPV1.

A physically smaller, less hydrophobic version of the lidocaine derivative QX314 designed to be more permeable to the TRPV1 ion channel for selective analgesia through TRPV1.

A physically smaller, less hydrophobic version of the lidocaine derivative QX314 designed to be more permeable to the TRPV1 ion channel for selective analgesia through TRPV1.

A potent EP4 agonist, triggering cAMP signaling with an EC₅₀ value of 0.8 nM.

A potent EP4 agonist, triggering cAMP signaling with an EC₅₀ value of 0.8 nM.

A selective inhibitor of 12-LO with an IC₅₀ value of 5.1 &microM.

A selective inhibitor of 12-LO with an IC₅₀ value of 5.1 &microM.

A selective inhibitor of 12-LO with an IC₅₀ value of 5.1 &microM.

An orally bioavailable inhibitor of mPGES-1 (IC₅₀ = 0.24 &microM in an in vitro human whole blood assay) inactive against COX-1 and COX-2 (9% inhibition at 100 &microM and 16% at 30 &microM, respectively).

An orally bioavailable inhibitor of mPGES-1 (IC₅₀ = 0.24 &microM in an in vitro human whole blood assay) inactive against COX-1 and COX-2 (9% inhibition at 100 &microM and 16% at 30 &microM, respectively).