Hydrocortamate

Biochem/physiol Actions GT949 is a potent and selective positive allosteric modulator (PAM) of the excitatory amino acid transporter EAAT2 (glutamate uptake EC 50 = 0.26 nM: COS-7 EAAT2 transfectant), but not EAAT1 or EAAT3.

A nucleotide that upon phosphorylation to GTP becomes incorporated into RNA used to study modulation of glutamatergic neurotransmission.

A nucleotide that upon phosphorylation to GTP becomes incorporated into RNA used to study modulation of glutamatergic neurotransmission.

A nucleotide that upon phosphorylation to GTP becomes incorporated into RNA used to study modulation of glutamatergic neurotransmission.

A nucleotide that upon phosphorylation to GTP becomes incorporated into RNA used to study modulation of glutamatergic neurotransmission.

L-glutamate is the major excitatory neurotransmitter in mammalian central nervous system (CNS). It interacts with membrane bound glutamate receptors.

L-glutamate is the major excitatory neurotransmitter in mammalian central nervous system (CNS). It interacts with membrane bound glutamate receptors.

L-glutamate is the major excitatory neurotransmitter in mammalian central nervous system (CNS). It interacts with membrane bound glutamate receptors.