Pyrithione zinc

InformationTHZ2, a THZ1 analog, is a selective inhibitor ofCDK7with IC50 of 13.9 nM. THZ2 efficiently suppresses the clonogenic growth of TNBC cells with IC50 of ~10 nM.TargetsCDK7 (Cell-free assay) 13.9 nMIn vitroTHZ2 selectively targets CDK7 and

InformationTHZ2, a THZ1 analog, is a selective inhibitor ofCDK7with IC50 of 13.9 nM. THZ2 efficiently suppresses the clonogenic growth of TNBC cells with IC50 of ~10 nM.TargetsCDK7 (Cell-free assay) 13.9 nMIn vitroTHZ2 selectively targets CDK7 and

InformationTHZ2, a THZ1 analog, is a selective inhibitor ofCDK7with IC50 of 13.9 nM. THZ2 efficiently suppresses the clonogenic growth of TNBC cells with IC50 of ~10 nM.TargetsCDK7 (Cell-free assay) 13.9 nMIn vitroTHZ2 selectively targets CDK7 and

A metal ion chelator used in zinc treatment studies to limit intra- and extracellular concentrations of the mineral.

A metal ion chelator used in zinc treatment studies to limit intra- and extracellular concentrations of the mineral.

A metal ion chelator used in zinc treatment studies to limit intra- and extracellular concentrations of the mineral.

A metal ion chelator used in zinc treatment studies to limit intra- and extracellular concentrations of the mineral.

TSQ is a cytosolic zinc fluorescence probe that is membrane permeable and can be used for intracellular imaging of zinc proteins (λmax ~470 nm). TSQ can combine with Zn2+ in the presence of Ca2+ and Mg2+ to produce blue fluorescence.

TSQ is a cytosolic zinc fluorescence probe that is membrane permeable and can be used for intracellular imaging of zinc proteins (λmax ~470 nm). TSQ can combine with Zn2+ in the presence of Ca2+ and Mg2+ to produce blue fluorescence.

TZ9 is a selective Rad6 inhibitor. TZ9 inhibits Rad6B -induced histone H2A ubiquitination, downregulates intracellular β-catenin , induces G2-M arrest and apoptosis , and inhibits the proliferation and migration of metastatic human breast cancer

TZ9 is a selective Rad6 inhibitor. TZ9 inhibits Rad6B -induced histone H2A ubiquitination, downregulates intracellular β-catenin , induces G2-M arrest and apoptosis , and inhibits the proliferation and migration of metastatic human breast cancer

TZ9 is a selective Rad6 inhibitor. TZ9 inhibits Rad6B -induced histone H2A ubiquitination, downregulates intracellular β-catenin , induces G2-M arrest and apoptosis , and inhibits the proliferation and migration of metastatic human breast cancer