Drugs affecting the gastrointestinal system

(±)11-HDoHE is an autoxidation product of docosahexaenoic acid (DHA) in vitro (1,2) and also produced from incubations of DHA in rat brain, intestinal microsomes and liver.3,4,5 DHA is metabolized to 11(S)-HDoHE by human platelets and canine

(±)11-HDoHE is an autoxidation product of docosahexaenoic acid (DHA) in vitro (1,2) and also produced from incubations of DHA in rat brain, intestinal microsomes and liver.3,4,5 DHA is metabolized to 11(S)-HDoHE by human platelets and canine

The 12,13-cis epoxide of linoleic acid, generated by neutrophils during the oxidative burst. The toxicity and biosynthesis of (±)12(13)-EpOME have not been well differentiated from (±)9(10)-EpOME, but are assumed to be essentially the

The 12,13-cis epoxide of linoleic acid, generated by neutrophils during the oxidative burst. The toxicity and biosynthesis of (±)12(13)-EpOME have not been well differentiated from (±)9(10)-EpOME, but are assumed to be essentially the

(±)12-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The biological activity of (±)12-HETE is similar to that of its constituent enantiomers. It aggregates neutrophils with an EC50 value

(±)12-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The biological activity of (±)12-HETE is similar to that of its constituent enantiomers. It aggregates neutrophils with an EC50 value

(±)12-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The biological activity of (±)12-HETE is similar to that of its constituent enantiomers. It aggregates neutrophils with an EC50 value

One of the six monohydroperoxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid and consists of an equivalent mixture of the R and S isomers. Reduction of the hydroperoxide yields the more stable hydroxyl fatty acid

One of the six monohydroperoxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid and consists of an equivalent mixture of the R and S isomers. Reduction of the hydroperoxide yields the more stable hydroxyl fatty acid

Produced by non-enzymatic oxidation of EPA, it contains equal amounts of 15(S) and 15(R)-HEPE. Specific biological activity attributed to this chemical has not been documented.

Produced by non-enzymatic oxidation of EPA, it contains equal amounts of 15(S) and 15(R)-HEPE. Specific biological activity attributed to this chemical has not been documented.

Produced by non-enzymatic oxidation of EPA, it contains equal amounts of 15(S) and 15(R)-HEPE. Specific biological activity attributed to this chemical has not been documented.