Amylase/dehydrocholic acid/protease

A single enantiomer of a potent and selective inactivator of KIAA1363, a MAGE hydrolase an enzyme that is upregulated in aggressive cancers from various tissues (IC50 = 150 nM when tested as a racemic mixture in SK0V-3 cells) activity of the

A single enantiomer of a potent and selective inactivator of KIAA1363, a MAGE hydrolase an enzyme that is upregulated in addressive cancers from various tissues (IC₅₀ = 150 nM when tested as a racemic mixture in SK0V-3 cells) activity of

A single enantiomer of a potent and selective inactivator of KIAA1363, a MAGE hydrolase an enzyme that is upregulated in addressive cancers from various tissues (IC₅₀ = 150 nM when tested as a racemic mixture in SK0V-3 cells) activity of

A single enantiomer of a potent and selective inactivator of KIAA1363, a MAGE hydrolase an enzyme that is upregulated in addressive cancers from various tissues (IC₅₀ = 150 nM when tested as a racemic mixture in SK0V-3 cells) activity of

(-)-Epigallocatechin Gallate (EGCG) is a strong polyphenol catechin antioxidant found in green tea, reported to have broad efficacy against many conditions generated from oxidative damage. Extensive oxidation of low density lipoproteins (LDLs) is cor

Application (2-(Piperidin-4-yl)phenyl)methanamine dihydrochloride is a 4-aryl piperidine useful as a semi-flexible linker in PROTAC development for targeted protein degradation . Incorporation of rigidity into the linker region of bifunctional

General description Tetrahydrobiopterin is a natural cofactor for phenylalanine hydroxylase, tyrosine hydroxylase, tryptophan hydroxylase, nitric oxide synthase and alkylglycerol monooxygenase. Application (6R)-BH 4 has been used as a buffer

General description Tetrahydrobiopterin is a natural cofactor for phenylalanine hydroxylase, tyrosine hydroxylase, tryptophan hydroxylase, nitric oxide synthase and alkylglycerol monooxygenase. Application (6R)-BH 4 has been used as a buffer

General description Tetrahydrobiopterin is a natural cofactor for phenylalanine hydroxylase, tyrosine hydroxylase, tryptophan hydroxylase, nitric oxide synthase and alkylglycerol monooxygenase. Application (6R)-BH 4 has been used as a buffer

4-(Trifluoromethyl)phenylacetic acid undergoes diolefination mediated by mono- N -protected amino acid ligands in the presence of ethyl acrylate, Pd(OAc) 2 , KHCO 3 and t -amyl alcohol .

Application ( S , R , S )-AHPC-Me-C 5 -COOH is a functionalized von-Hippel-Lindau (VHL) ligand with a terminal carboxyl group, allowing rapid conjugation of amine containing linkers. A basic building block for development of a protein degrader

1 3-DIFURFURYLUREA