Amylase/papain

InformationY16 Y16 is an inhibitor of G-protein-coupled Rho GEFs . It blocks the binding of LARG, a DBL-family Rho guanine nucleotide exchange factor, with Rho (Kd = 80 nM).TargetsRhoGEFsIn vitroY16 binds to the junction site of the DH-PH domains of

InformationY16 Y16 is an inhibitor of G-protein-coupled Rho GEFs . It blocks the binding of LARG, a DBL-family Rho guanine nucleotide exchange factor, with Rho (Kd = 80 nM).TargetsRhoGEFsIn vitroY16 binds to the junction site of the DH-PH domains of