Atropine/difenoxin

A hybrid molecule of an H2S donor and the NSAID indomethacin that does not cause gastric damage or promote leukocyte adherence to vascular endothelium.

ATB-346 is a non-steroidal anti-inflammatory drug (NSAID), derived from naproxen but coupled to an H₂S-releasing moiety. At 30 &micromol/kg in rats, it suppressed COX and gastric PGE₂ synthesis to the same level as naproxen

ATB-346 is a non-steroidal anti-inflammatory drug (NSAID), derived from naproxen but coupled to an H₂S-releasing moiety. At 30 &micromol/kg in rats, it suppressed COX and gastric PGE₂ synthesis to the same level as naproxen

ATB-346 is a non-steroidal anti-inflammatory drug (NSAID), derived from naproxen but coupled to an H₂S-releasing moiety. At 30 &micromol/kg in rats, it suppressed COX and gastric PGE₂ synthesis to the same level as naproxen

Biochem/physiol Actions ATC0175 is a non-peptide, orally active melanin-concentrating hormone receptor 1 (MCHR1) antagonist. Non-peptide, orally active melanin-concentrating hormone receptor 1 (MCHR1) antagonist.

ATH3G10 (anti-Phosphorylcholine) is a antibody targeting phosphorylcholine (PC).They are known to contribute to the immune defense against a variety of microbial infections.

ATH3G10 (anti-Phosphorylcholine) is a antibody targeting phosphorylcholine (PC).They are known to contribute to the immune defense against a variety of microbial infections.

ATH3G10 (anti-Phosphorylcholine) is a antibody targeting phosphorylcholine (PC).They are known to contribute to the immune defense against a variety of microbial infections.

ATH3G10 (anti-Phosphorylcholine) is a antibody targeting phosphorylcholine (PC).They are known to contribute to the immune defense against a variety of microbial infections.

Biochemical MechanismATI-2341 is a potent and selective allosteric agonist of chemokine CXC-type receptor 4 (CXCR4) that functions as a biased ligand, favoring Gαi activation over Gα13. ATI-2341 does not promote β-arrestin recruitment. ATI-2341

Biochemical MechanismATI-2341 is a potent and selective allosteric agonist of chemokine CXC-type receptor 4 (CXCR4) that functions as a biased ligand, favoring Gαi activation over Gα13. ATI-2341 does not promote β-arrestin recruitment. ATI-2341

Biochemical MechanismATI-2341 is a potent and selective allosteric agonist of chemokine CXC-type receptor 4 (CXCR4) that functions as a biased ligand, favoring Gαi activation over Gα13. ATI-2341 does not promote β-arrestin recruitment. ATI-2341