Bisoxatin acetate

(R)-BAY1238097 is the R-isomer with lower activity of BAY1238097. BAY1238097 is a potent and selective inhibitor of BET binding to histones and has strong anti-proliferative activity in different AML (acute myeloid leukemia) and MM (multiple

(R)-BAY1238097 is the R-isomer with lower activity of BAY1238097. BAY1238097 is a potent and selective inhibitor of BET binding to histones and has strong anti-proliferative activity in different AML (acute myeloid leukemia) and MM (multiple

(R)-BAY1238097 is the R-isomer with lower activity of BAY1238097. BAY1238097 is a potent and selective inhibitor of BET binding to histones and has strong anti-proliferative activity in different AML (acute myeloid leukemia) and MM (multiple

(R)-BAY1238097 is the R-isomer with lower activity of BAY1238097. BAY1238097 is a potent and selective inhibitor of BET binding to histones and has strong anti-proliferative activity in different AML (acute myeloid leukemia) and MM (multiple

Biochem/physiol Actions ABC1183 is an orally active, potent and selective inhibitor of GSK3 &#945:/&#946: and CDK9, which induces G2/M cell cycle arrest and apoptosis in cancer cells. Apparently ABC1183 suppresses tumor growth and

A cell-permeable and selective inhibitor of human Acetyl-CoA carboxylase 2 (ACC2) (IC 50 = 2.8 &#181M), which does not inhibit human ACC1 at all at concentrations up to 100 &#181M, in vitro .

BRG1-associated factor 180 (BAF180) is a subunit of the SWI/SNF-B (PBAF) chromatin remodeling complex, and is known to contain 6 bromo domains, 2 BAH domains, and a single HMG box DNA-binding domain. BAF180 has a critical and active role in the

Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. Histones are modified post-translationally by the actions of enzymes in both the nucleus and cytoplasm.

Biochem/physiol Actions BAZ2-ICR is a chemical probe for BAZ2A/B bromodomains with &gt:100-fold selectivity over other bromodomains, with the exception of CECR2 (15-fold selectivity). BAZ2A is an essential component of the nucleolar remodeling

Biochem/physiol Actions BAZ2-ICR is a chemical probe for BAZ2A/B bromodomains with &gt:100-fold selectivity over other bromodomains, with the exception of CECR2 (15-fold selectivity). BAZ2A is an essential component of the nucleolar remodeling

Bis(4-methoxybenzylidene)acetone.

BIS(4-METHOXYBENZYLIDENE)ACETONE-