Calcium carbonate/calcium phosphate

CAY10416 is a dual COX-2/5-LO inhibitor with IC₅₀ values of 50 and 3 nM, respectively. The selectivity of CAY10416 for COX is greater than 200-fold for COX-2 versus COX-1.

Biochem/physiol Actions CAY10444 is a selective sphingosine-1-phosphate (S1P) receptor 3 (S1P3: EDG3) antagonist that inhibits 1 &#181:M S1P-induced calcium mobilization in HeLa transfectants that express S1P3 over those expressing S1P1/CD363/EDG1

Biochem/physiol Actions CAY10444 is a selective sphingosine-1-phosphate (S1P) receptor 3 (S1P3: EDG3) antagonist that inhibits 1 &#181:M S1P-induced calcium mobilization in HeLa transfectants that express S1P3 over those expressing S1P1/CD363/EDG1

A selective antagonist of S1P binding to the S1P3 receptor blocks calcium increase in HeLa cells by about 40% at 10 &microM.

A selective antagonist of S1P binding to the S1P3 receptor blocks calcium increase in HeLa cells by about 40% at 10 &microM.

A selective antagonist of S1P binding to the S1P3 receptor blocks calcium increase in HeLa cells by about 40% at 10 &microM.

A selective antagonist of S1P binding to the S1P3 receptor blocks calcium increase in HeLa cells by about 40% at 10 &microM.

CAY10506 is a peroxisome proliferator-activated receptor γ (PPARγ) agonist, a nuclear transcription factor that controls lipid homeostasis and glucose metabolism.

A hybrid lipoic acid-TZD derivative that transactivates human PPAR&gamma with an EC50 value of 10 &microM.

A hybrid lipoic acid-TZD derivative that transactivates human PPAR&gamma with an EC50 value of 10 &microM.

A hybrid lipoic acid-TZD derivative that transactivates human PPAR&gamma with an EC50 value of 10 &microM.

A S-nitrosothiol that acts as an NO donor under acidic conditions decomposes with a half-life of 6 minutes in 0.1 M phosphate buffer, pH 5.