Cyclizine

2-Imino-1-imidazolidineacetic acid (cyclocreatine) is an analog of creatine. It is reported to exhibit antitumour effect in some transplanted human and rodent tumours in vivo .

A mechanism-based inactivator of human CYP2B6 (Ki = 5.6 &microM IC₅₀ = 5.1 &microM) with potent selectivity for CYP2B6 over other CYP450 isoforms.

CYP2C19 metabolite of mephenytoin. Application Pharmacological activity investigating: The drug effects on metabolization In vitro cytochrome P450 activity in microsomes Analyte for electron-capture gas chromatography procedures

A cell-permeable inhibitor of lipopolysaccaride (LPS)-induced synthesis of tumor necrosis factor-&#945 and nitric oxide in murine peritoneal macrophages. Blocks LPS-induced tyrosine phosphorylation of a p42 MAPK protein substrate.

A broad-spectrum protein tyrosine kinase inhibitor. Inhibits epidermal growth factor receptor autophosphorylation (IC 50 = 40 &#181M) and the GTPase activity of transducin (IC 50 = 10 &#181M).

Alsterpaullone, 2-Cyanoethyl is an alsterpaullone derivative that acts as a highly potent, ATP-competitive, selective inhibitor of Cdk1/cyclin B and GSK-3β (IC50 = 230 pM and 800 pM, respectively: [ATP] = 15 μM). Alsterpaullone, 2-Cyanoethyl

General description The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK

Specificity Clone 10D1 is a mouse monoclonal antibody that detects CXCR7. It targets an epitope within the extracellular domain.

General description C-C motif chemokine ligand 2 (CCL2) gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes.

Anti-CCNB1 cyclin B1, 25ul UN 1687 6.1 PG2

Anti-CCNB1 cyclin B1, 25ul UN 1687 6.1 PG2

CCNB3 is a highly conserved cyclin protein that may be involved in cell cycle regulation. CCNB3-BCOR fusion genes have been linked to bone sarcoma.