Darifenacin or darifenacin hydrobromide

InformationBFH772 is a novel potent oralVEGFR2inhibitor, targeting VEGFR2 kinase with IC50 of 3 nM.TargetsVEGFR2 (Cell-free assay) 3 nMIn vitroBFH772 was highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM, however, lost 500-fold

BRD9757 is a potent, capless and selective HDAC6 inhibitor with an IC50 of 30 nM. BRD9757 shows excellent selectivity toward HDAC6 versus the class I (&gt:20-fold) and class II (&gt:400-fold) HDACs.

BRD9757 is a potent, capless and selective HDAC6 inhibitor with an IC50 of 30 nM. BRD9757 shows excellent selectivity toward HDAC6 versus the class I (&gt:20-fold) and class II (&gt:400-fold) HDACs.

BRD9757 is a potent, capless and selective HDAC6 inhibitor with an IC50 of 30 nM. BRD9757 shows excellent selectivity toward HDAC6 versus the class I (&gt:20-fold) and class II (&gt:400-fold) HDACs.

BRD9757 is a potent, capless and selective HDAC6 inhibitor with an IC50 of 30 nM. BRD9757 shows excellent selectivity toward HDAC6 versus the class I (&gt:20-fold) and class II (&gt:400-fold) HDACs.

An HDAC inhibitor (IC₅₀s = 29 nM, 62 nM, and 1.09 &microM for HDAC1, 2, and 3, respectively) possesses preferential binding kinetics with seven-fold longer half-life on HDAC2 compared to HDAC1 (143 min vs. 20 min).

An HDAC inhibitor (IC₅₀s = 29 nM, 62 nM, and 1.09 &microM for HDAC1, 2, and 3, respectively) possesses preferential binding kinetics with seven-fold longer half-life on HDAC2 compared to HDAC1 (143 min vs. 20 min).

An HDAC inhibitor (IC₅₀s = 29 nM, 62 nM, and 1.09 &microM for HDAC1, 2, and 3, respectively) possesses preferential binding kinetics with seven-fold longer half-life on HDAC2 compared to HDAC1 (143 min vs. 20 min).

An HDAC inhibitor (IC₅₀s = 29 nM, 62 nM, and 1.09 &microM for HDAC1, 2, and 3, respectively) possesses preferential binding kinetics with seven-fold longer half-life on HDAC2 compared to HDAC1 (143 min vs. 20 min).

A small molecule inhibitor that potently and selectively inhibits both HDAC6 and HDAC8 (IC₅₀s = 36 and 120 nM, respectively).

A small molecule inhibitor that potently and selectively inhibits both HDAC6 and HDAC8 (IC₅₀s = 36 and 120 nM, respectively).

InformationBrefeldin A Brefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces cancer cell differentiation and apoptosis . It could also improve the HDR(homology-directed repair)