Drofenine hydrochloride

5,6-Diamino-1,3-diethyluracil Hydrochloride.

5,6-Diamino-1,3-diethyluracil Hydrochloride.

5,6-Diamino-1,3-diethyluracil Hydrochloride.

A potent inhibitor of DGAT-1 (IC50s = 7 and 24 nM, for human and mouse, respectively) confers significant weight loss within seven days and significantly reduces plasma and liver triglycerides when administered at 3 mg/kg to DIO mice.

A potent inhibitor of DGAT-1 (IC50s = 7 and 24 nM, for human and mouse, respectively) confers significant weight loss within seven days and significantly reduces plasma and liver triglycerides when administered at 3 mg/kg to DIO mice.

DPYD is an important enzyme involved in pyrimidine base degradation and catabolism. DPYD catalyzes the reduction of uracil and thymine and also is a critical enzyme in the degradation of the chemotherapeutic drug 5-fluoruracil.

General description Leucine-rich repeats and immunoglobulin-like domains protein 1 (UniProt: Q96JA1: also known as LIG-1) is encoded by the LRIG1 (also known as LIG1) gene (Gene ID: 26018) in human. LIG-1 is a widely expressed single-pass type I

General description Leucine-rich repeats and immunoglobulin-like domains protein 1 (UniProt: Q96JA1: also known as LIG-1) is encoded by the LRIG1 (also known as LIG1) gene (Gene ID: 26018) in human. LIG-1 is a widely expressed single-pass type I

General description Breast cancer type 1 susceptibility protein (UniProt: P38398: also known as EC:2.3.

General description Breast cancer type 1 susceptibility protein (UniProt: P38398: also known as EC:2.3.

A potent inhibitor of B-RafV600E (Kd = 14 nM in an in vitro binding assay) blocks B-RafV600E&ndashdependent phosphorylation of MEK in human melanoma A375 and colorectal cancer COLO 205 cells (IC₅₀s = 78 and 60 nM, respectively)

A potent inhibitor of B-RafV600E (Kd = 14 nM in an in vitro binding assay) blocks B-RafV600E&ndashdependent phosphorylation of MEK in human melanoma A375 and colorectal cancer COLO 205 cells (IC₅₀s = 78 and 60 nM, respectively)