Eperisone hydrochloride

MISSION &#174 esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence.

General description This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events,

General description Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in

Biochem/physiol Actions ONO-AE3-208 is an orally active prostaglandin E2 receptor 4 (EP4)-selective antagonist (Ki in nM = 1.3/EP4, 30/EP3, 790/FP and 2400/TP: Ki &gt:10 &#956:M for prostanoid receptors DP, EP1, EP2, IP).

Biochem/physiol Actions ONO-AE3-208 is an orally active prostaglandin E2 receptor 4 (EP4)-selective antagonist (Ki in nM = 1.3/EP4, 30/EP3, 790/FP and 2400/TP: Ki &gt:10 &#956:M for prostanoid receptors DP, EP1, EP2, IP).

A highly potent, reversible inhibitor of the EGFR (Ki = 5.2 pM IC₅₀ = 29 pM) rapidly suppresses autophosphorylation of EGFR in ?broblasts and human epidermoid carcinoma cells.

A highly potent, reversible inhibitor of the EGFR (Ki = 5.2 pM IC₅₀ = 29 pM) rapidly suppresses autophosphorylation of EGFR in ?broblasts and human epidermoid carcinoma cells.

A reversible ERK1/2 inhibitor (IC₅₀ value of 180 nM).