Proglumide

PGF2&alpha dimethyl amine is a derivative of PGF2&alpha which was designed as a PG antagonist for in vitro and in vivo studies. PGF2&alpha dimethyl amine is a weak FP receptor antagonist.

PGF2&alpha dimethyl amine is a derivative of PGF2&alpha which was designed as a PG antagonist for in vitro and in vivo studies. PGF2&alpha dimethyl amine is a weak FP receptor antagonist.

PGF2&alpha dimethyl amine is a derivative of PGF2&alpha which was designed as a PG antagonist for in vitro and in vivo studies. PGF2&alpha dimethyl amine is a weak FP receptor antagonist.

A derivative of PGF2α that was designed as a PG antagonist for in vitro and in vivo studies. A weak FP receptor antagonist. In gerbil colon, PGF2α dimethyl amine at a dose of 3.2 µg/ml inhibits the contractile effects of PGF2α (at 6 ng/ml) by 60%

A derivative of PGF2α that was designed as a PG antagonist for in vitro and in vivo studies. A weak FP receptor antagonist. In gerbil colon, PGF2α dimethyl amine at a dose of 3.2 µg/ml inhibits the contractile effects of PGF2α (at 6 ng/ml) by 60%

PGG2 is the first intermediate in the COX pathway which is stable enough to be isolated and characterized. It is the C-15 hydroperoxide of PGH2.

PGH1 is a COX metabolite of DGLA and is the precursor to all 1-series PGs and thromboxanes. PGH1 is a suicide inhibitor of platelet thromboxane synthase with a Ki of 28 &microM.

A COX metabolite of arachidonic acid and precursor for all 2-series ,PGs and TXs acts as a TP receptor agonist and suicide substrate for TX synthase (Ki = 18 &microM).

Prostaglandin I2 sodium

A dehydration product of PGD2 formed by the elimination of the C-9 hydroxyl group inhibits platelet aggregation (IC₅₀ ~ 5-10 nM) has antimitotic and antiproliferative effects on a variety of cultured normal cells and tumor cell lines.

PROTAC BRD4 Degrader-8 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 , with IC 50 s of 1.1 nM and 1.4 nM for BRD4 BD1 and BD2 , respectively. PROTAC BRD4 Degrader-8 is capable of potently degrading the BRD4 protein in PC3 prostate

PROTAC BRD4 Degrader-8 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 , with IC 50 s of 1.1 nM and 1.4 nM for BRD4 BD1 and BD2 , respectively. PROTAC BRD4 Degrader-8 is capable of potently degrading the BRD4 protein in PC3 prostate