Almitrine dimesilate

Ensifentrine (RPL-554) is an inhaled first-in-class dual inhibitor of phosphodiesterase 3 (PDE3) and PDE4 with IC 50 s of 0.4 nM and 1479 nM, respectively. Ensifentrine has bronchoprotective and anti-inflammatory activities. Ensifentrine can be used

Ensifentrine (RPL-554) is an inhaled first-in-class dual inhibitor of phosphodiesterase 3 (PDE3) and PDE4 with IC 50 s of 0.4 nM and 1479 nM, respectively. Ensifentrine has bronchoprotective and anti-inflammatory activities. Ensifentrine can be used

Ensifentrine (RPL-554) is an inhaled first-in-class dual inhibitor of phosphodiesterase 3 (PDE3) and PDE4 with IC 50 s of 0.4 nM and 1479 nM, respectively. Ensifentrine has bronchoprotective and anti-inflammatory activities. Ensifentrine can be used

InformationGNE-617 GNE-617 is a highly potent inhibitor of NAMPT activity with an IC50 of 5 nM.TargetsNAMPT (Cell-free assay) 5 nM.

InformationGNE-617 GNE-617 is a highly potent inhibitor of NAMPT activity with an IC50 of 5 nM.TargetsNAMPT (Cell-free assay) 5 nM.

InformationGNE-617 GNE-617 is a highly potent inhibitor of NAMPT activity with an IC50 of 5 nM.TargetsNAMPT (Cell-free assay) 5 nM.

J 104129 is a potent mAChR M3 antagonist that displays ~ 120-fold selectivity over mAChR M2 (K|i|values are 4.2, 19 and 490 nM for human mAChR M3, mAChR M1 and mAChR M2 receptors, respectively). J 104129 exhibits &gt: 250-fold bronchial selectivity.

Lixivaptan (VPA-985, WAY-VPA 985) is an orally active and selective vasopressin receptor V2 antagonist, with IC50 values of 1.2 and 2.

Lixivaptan (VPA-985, WAY-VPA 985) is an orally active and selective vasopressin receptor V2 antagonist, with IC50 values of 1.2 and 2.

Lixivaptan (VPA-985, WAY-VPA 985) is an orally active and selective vasopressin receptor V2 antagonist, with IC50 values of 1.2 and 2.

Lixivaptan (VPA-985, WAY-VPA 985) is an orally active and selective vasopressin receptor V2 antagonist, with IC50 values of 1.2 and 2.

Lixivaptan (VPA-985, WAY-VPA 985) is an orally active and selective vasopressin receptor V2 antagonist, with IC50 values of 1.2 and 2.