Calcitonin

An internally quenched peptide substrate that is optimized for calpain-1 amino acid recognition motifs at the primed as well as the non-primed sides. Shown to be kinetically superior, in terms of turnover rate, to Calpain Substrate III, Fluorogenic

Native calpain-1 from porcine erythrocytes. Ca2+-dependent heterodimeric cysteine proteinase with low Ca2+ requirement (EC50= 2 µM).

Calpain-2-IN-1 (Formula 1A) is a isoform-specific calpain-2 inhibitor with K i s of 181 nM and 7.8 nM for calpain-1, and calpain-2, respectively. Calpain-2-IN-1 can be used for the research of neurodegenerative diseases and other diseases of

Calpain-2-IN-1 (Formula 1A) is a isoform-specific calpain-2 inhibitor with K i s of 181 nM and 7.8 nM for calpain-1, and calpain-2, respectively. Calpain-2-IN-1 can be used for the research of neurodegenerative diseases and other diseases of

A 27-amino acid, cell-permeable peptide encoded by exon 1B of human calpastatin that acts as a potent inhibitor of calpain I and calpain II (IC 50 = 20 nM for purified rabbit calpain II). Does not inhibit either papain or trypsin.

Amino Acid Sequence Ac-Asp-Pro-Met-Ser-Ser-Thr-Tyr-Ile-Glu-Glu-Leu-Gly-Lys-Arg-Glu-Val-Thr-Ile-Pro-Pro-Lys-Tyr-Arg-Glu-Leu-Leu-Ala-NH2 Application Calpastatin Peptide Ac 184-210 has been used as the endogenous calpain inhibitor to study its

Amino Acid Sequence Ac-Asp-Pro-Met-Ser-Ser-Thr-Tyr-Ile-Glu-Glu-Leu-Gly-Lys-Arg-Glu-Val-Thr-Ile-Pro-Pro-Lys-Tyr-Arg-Glu-Leu-Leu-Ala-NH2 Application Calpastatin Peptide Ac 184-210 has been used as the endogenous calpain inhibitor to study its

Calpeptin (Z-Leu-nLeu-H) is a cell permeable, peptide aldehyde inhibitor. It is more sensitive to calpain I compared to other inhibitors, such as Z-Leu-Met-H and leupeptin.

Calpeptin (Z-Leu-nLeu-H) is a cell permeable, peptide aldehyde inhibitor. It is more sensitive to calpain I compared to other inhibitors, such as Z-Leu-Met-H and leupeptin.

General description A cell-permeable calpain inhibitor (ID 50 = 52 nM for calpain-1: ID 50 = 34 nM for calpain-2: ID 50 = 138 nM for papain). Inhibits the Ca 2+ -stimulated cleavage of p35 to p25 by calpain.

General description A cell-permeable calpain inhibitor (ID 50 = 52 nM for calpain-1: ID 50 = 34 nM for calpain-2: ID 50 = 138 nM for papain). Inhibits the Ca 2+ -stimulated cleavage of p35 to p25 by calpain.

General description A cell-permeable calpain inhibitor (ID 50 = 52 nM for calpain-1: ID 50 = 34 nM for calpain-2: ID 50 = 138 nM for papain). Inhibits the Ca 2+ -stimulated cleavage of p35 to p25 by calpain.