Ciglitazone

An antidiabetic drug and selective PPAR&gamma agonist (EC₅₀ = 3.0 &microM) active in vivo as an anti-hyperglycemic agent the ob/ob mouse model.

General description This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the

General description This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the

General description This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the

Synonym(s): N-Cyclohexyl-N-methyl-4-(1,2-dihydro-2-oxo-6-quinolyloxy)butyramide, OPC 3689 Formula: C20H26N2O3 Formula weight: 342.43 CAS Number: 68550-75-4 Harmonized Tariff Code:  3822.00

Cilostazol is a potent cyclic nucleotide phosphodiesterase inhibitor. It is mainly used as antiplatelet agent.

Cimaterol (CL 263780) is a β-adrenergic agonist on energy metabolism in ob/ob mice. The Kd for Cimaterol binding to the L6 β-receptor is 26 nM which is compatible with its EC50 for the stimulation of protein synthesis (approx 5 nM).

Cimaterol (CL 263780) is a β-adrenergic agonist on energy metabolism in ob/ob mice. The Kd for Cimaterol binding to the L6 β-receptor is 26 nM which is compatible with its EC50 for the stimulation of protein synthesis (approx 5 nM).

Cimaterol (CL 263780) is a β-adrenergic agonist on energy metabolism in ob/ob mice. The Kd for Cimaterol binding to the L6 β-receptor is 26 nM which is compatible with its EC50 for the stimulation of protein synthesis (approx 5 nM).

A potent agonist of &beta-adrenergic receptors (pEC₅₀ = 8.13, 8.78, and 6.62 for human &beta1, &beta2, and &beta3, respectively).

A potent agonist of &beta-adrenergic receptors (pEC₅₀ = 8.13, 8.78, and 6.62 for human &beta1, &beta2, and &beta3, respectively).

Biochem/physiol Actions CINK4 is a specific inhbitor of CDK4/cyclin D1 complexes (IC 50 = 1.5 mM).