Epimestrol

(R)-Equol is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzein by human intestinal microflora. It is a chiral molecule that exists in two enantiomeric forms. In contrast to the estrogen receptor

A homolog of EPEA, characterized by the addition of an (S)-&beta-methyl group at the terminal ethanolamine carbon.

A homolog of EPEA, characterized by the addition of an (S)-&alpha-methyl group at the methylene carbon adjacent to the amide nitrogen.

A homolog of EPEA, characterized by the addition of an (S)-&alpha-methyl group at the methylene carbon adjacent to the amide nitrogen.

A homolog of EPEA, characterized by the addition of an (S)-&alpha-methyl group at the methylene carbon adjacent to the amide nitrogen.

The naturally occurring enantiomer of equol that demonstrates ER agonist activity similar to that of genistein (EC50 = 85 and 65 nM for human ER&alpha and ER&beta, respectively) preferentially binds ER&beta (Ki = 0.73 nM) with lower affinity for

The naturally occurring enantiomer of equol that demonstrates ER agonist activity similar to that of genistein (EC50 = 85 and 65 nM for human ER&alpha and ER&beta, respectively) preferentially binds ER&beta (Ki = 0.73 nM) with lower affinity for

The naturally occurring enantiomer of equol that demonstrates ER agonist activity similar to that of genistein (EC50 = 85 and 65 nM for human ER&alpha and ER&beta, respectively) preferentially binds ER&beta (Ki = 0.73 nM) with lower affinity for

The naturally occurring enantiomer of equol that demonstrates ER agonist activity similar to that of genistein (EC50 = 85 and 65 nM for human ER&alpha and ER&beta, respectively) preferentially binds ER&beta (Ki = 0.73 nM) with lower affinity for

EDHF (endothelium-derived hyperpolarizing factor), an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin, is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators.

EDHF (endothelium-derived hyperpolarizing factor), an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin, is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators.

15(R)-Prostaglandin E2 is the C-15 epimer of the naturally occurring 15(S)-PGE2 isomer: the most physiologically abundant eicosanoid, which is produced predominantly from arachidonic acid by COX and PGES, and exists at some level in nearly all