Glimepiride/pioglitazone

The precursor of OEA, an endogenous, potent agonist for PPAR&alpha (EC50 = 120 nM) OEA suppresses food intake and reduces weight gain in rats and PPAR&alpha wild-type mice, but not in PPAR&alpha knockout mice.

The precursor of OEA, an endogenous, potent agonist for PPAR&alpha (EC50 = 120 nM) OEA suppresses food intake and reduces weight gain in rats and PPAR&alpha wild-type mice, but not in PPAR&alpha knockout mice.

GLYCOGEN Controls /Pk(25)

Components Contains 10 mg each of the glycolysis and gluconeogenesis pathway metabolite standards packaged individually.

A selective, brain-penetrable LRRK2 inhibitor (Ki = 0.7 nM) inhibits LRRK2 Ser1292 autophosphorylation in BAC transgenic mice expressing human LRRK2 protein with the G2019S Parkinson&rsquos disease mutation (IC₅₀ = 3 nM in vivo).

A selective, brain-penetrable LRRK2 inhibitor (Ki = 0.7 nM) inhibits LRRK2 Ser1292 autophosphorylation in BAC transgenic mice expressing human LRRK2 protein with the G2019S Parkinson&rsquos disease mutation (IC₅₀ = 3 nM in vivo).

InformationGNE-490 is a highly selective pan-PI3K inhibitor that demonstrates selectivity over mTOR.

InformationGNE-490 is a highly selective pan-PI3K inhibitor that demonstrates selectivity over mTOR.

InformationGNE-490 is a highly selective pan-PI3K inhibitor that demonstrates selectivity over mTOR.

InformationGNE-490 is a highly selective pan-PI3K inhibitor that demonstrates selectivity over mTOR.

InformationGNE-490 is a highly selective pan-PI3K inhibitor that demonstrates selectivity over mTOR.

InformationGNE-490 is a highly selective pan-PI3K inhibitor that demonstrates selectivity over mTOR.