Glimepiride/pioglitazone

RG-13022 is a Tyrosine kinase tyrphostin. Reports indicate that RG-13022 suppresses epidermal growth factor (EGF)-stimulated cancer cell proliferation in cancer cell studies. Additionally, RG-13022 has been described to inhibit EGF, platelet-dervied

RG-13022 is a Tyrosine kinase tyrphostin. Reports indicate that RG-13022 suppresses epidermal growth factor (EGF)-stimulated cancer cell proliferation in cancer cell studies. Additionally, RG-13022 has been described to inhibit EGF, platelet-dervied

An inhibitor of EGF receptor kinase with an IC50 value of 1 &microM in HT-22 cells.

An inhibitor of EGF receptor kinase with an IC50 value of 1 &microM in HT-22 cells.

Biochem/physiol Actions Ridaforolimus is an antiproliferative mTOR inhibitor that forms a complex with the FK506 binding protein-12 (FKBP-12), which binds to and inhibits mTOR resulting in cell cycle arrest and inhibition of tumor cell growth and

Biochem/physiol Actions Ridaforolimus is an antiproliferative mTOR inhibitor that forms a complex with the FK506 binding protein-12 (FKBP-12), which binds to and inhibits mTOR resulting in cell cycle arrest and inhibition of tumor cell growth and

InformationRidaforolimus (Deforolimus, MK-8669) Ridaforolimus (Deforolimus, MK-8669, AP23573) is a selective mTOR inhibitor with IC50 of 0.2 nM in HT-1080 cell line: while not classified as a prodrug, mTOR inhibition and FKBP12 binding is similar to

Application SB 415286 was used to treat neuroblastoma cells and study the effect of GSK-3 inhibition on cell proliferation. Biochem/physiol Actions SB 415286 is a small molecule inhibitor of GSK-3 in muscle and fat cells.

Biochem/physiol Actions SB290157 is a selective antagonist of complement anaphylatoxin C3a receptor, a 74 amino acid proinflammatory peptide that is a potent chemotaxin for eosinophils, macrophages and mast cells, and has recently been found to be

Biochem/physiol Actions SB290157 is a selective antagonist of complement anaphylatoxin C3a receptor, a 74 amino acid proinflammatory peptide that is a potent chemotaxin for eosinophils, macrophages and mast cells, and has recently been found to be

SMAD2 Protein is stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.

Biochem/physiol Actions SPA70 is a cell penetrant, potent and highly selective human pregnane X receptor (hPXR) antagonist that inhibits hPXR in humanized mouse models. It inhibits hPXR-mediated drug metabolism in in primary human hepatocytes and