Glimepiride/pioglitazone

Biochem/physiol Actions SPA70 is a cell penetrant, potent and highly selective human pregnane X receptor (hPXR) antagonist that inhibits hPXR in humanized mouse models. It inhibits hPXR-mediated drug metabolism in in primary human hepatocytes and

Potent GAL2/3agonist: exhibits anxiolytic effectsin vivo.

The SPIRE2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SPIRE2. This antibody recognizes human, mouse, rat antigen.

sPLA2-IIA Inhibitor II, KH064, 10MG

ApplicationSR 16832 is a dual site PPARγ inhibitor. Acts at orthosteric and allosteric sites in the ligand binding domain. Inhibits binding of endogenous ligands and transcriptional activity of PPARγ, more effectively than the orthosteric covalent

Biochem/physiol Actions ST247 is a PPAR &#946:/&#948: selective inverse agonist. The compound is based on the structure of GSK0660, and is 10-fold more potent in blocking the transcription of endogenous target genes: ST247 IC 50 = 19 nm vs.

A cell-permeable and orally available diphenylbutylpiperidine class of psychotropic drug with antagonistic activity against DAT (dopamine transporter) as well as several postsynaptic receptors, including D 1 , D 2 , D 3 , D 4 , &#945 1 -/&#945 2

An inhibitor of GLUT1 (IC50 = ~1 &microM) that blocks glucose uptake and induces necrosis in cancer cells that lack VHL inhibits NAMPT, an enzyme that induces GLUT1 expression toxic to hPSCs and can be used to selectively eliminate hPSCs from

An inhibitor of GLUT1 (IC50 = ~1 &microM) that blocks glucose uptake and induces necrosis in cancer cells that lack VHL inhibits NAMPT, an enzyme that induces GLUT1 expression toxic to hPSCs and can be used to selectively eliminate hPSCs from

sTRAIL Receptor-2, TNFRSF10B, human: Tumor necrosis factor-related apoptosis-inducing ligand Receptor 2 (TRAIL-R2) is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell-death signaling.

sTRAIL Receptor-2, TNFRSF10B, human: Tumor necrosis factor-related apoptosis-inducing ligand Receptor 2 (TRAIL-R2) is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell-death signaling.

sTRAIL Receptor-2, TNFRSF10B, human: Tumor necrosis factor-related apoptosis-inducing ligand Receptor 2 (TRAIL-R2) is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell-death signaling.