Glimepiride/pioglitazone

MAGL/FAAH inhibitor.

MAGL/FAAH inhibitor.

MAGL/FAAH inhibitor.

MAGL/FAAH inhibitor.

MAGL/FAAH inhibitor.

MAGL/FAAH inhibitor.

A dual inhibitor of both PI3K and mTOR, completely blocking phosphorylation of substrates at 8-16 &microM induces cell death in GBM xenografts in vitro, with half maximal inhibition occurring at 3.7-7.

A dual inhibitor of both PI3K and mTOR, completely blocking phosphorylation of substrates at 8-16 &microM induces cell death in GBM xenografts in vitro, with half maximal inhibition occurring at 3.7-7.

A dual inhibitor of both PI3K and mTOR, completely blocking phosphorylation of substrates at 8-16 &microM induces cell death in GBM xenografts in vitro, with half maximal inhibition occurring at 3.7-7.

A dual inhibitor of both PI3K and mTOR, completely blocking phosphorylation of substrates at 8-16 &microM induces cell death in GBM xenografts in vitro, with half maximal inhibition occurring at 3.7-7.

A cell-permeable and selective inhibitor of PIKfyve (IC₅₀ = 33 nM) reversibly impairs endosomal trafficking in NIH3T3 cells and blocks retroviral exit by budding from cells inhibits basal and insulin-activated 2-deoxyglucose uptake