Metformin/pioglitazone

A natural inhibitor of exportin 1, preventing the export of proteins from the nucleus reduces several intracellular signaling pathways, including NF-&kappaB, impacting inflammation, cancer, viral replication, and other processes.

A natural inhibitor of exportin 1, preventing the export of proteins from the nucleus reduces several intracellular signaling pathways, including NF-&kappaB, impacting inflammation, cancer, viral replication, and other processes.

General description DKK-1 (dickkopf WNT signaling pathway inhibitor 1) is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. Recombinant human DKK-1 expressed in human 293 cells is a 35-40kDa glycoprotein containing

DMH1 stimulates neurogenesis of human-induced pluripotent stem cells (hiPSCs) and suppresses the growth and metastasis of lung cancer. It blocks cellular autophagy responses.

DMH1 stimulates neurogenesis of human-induced pluripotent stem cells (hiPSCs) and suppresses the growth and metastasis of lung cancer. It blocks cellular autophagy responses.

FOCUS™ Mammalian Proteome

FT709 is a potent and selective USP9X inhibitor, an IC 50 of 82 nM. USP9X has been linked with centrosome function, chromosome alignment during mitosis, EGF receptor degradation, chemo-sensitization, and circadian rhythms.Form:Solid.

FT709 is a potent and selective USP9X inhibitor, an IC 50 of 82 nM. USP9X has been linked with centrosome function, chromosome alignment during mitosis, EGF receptor degradation, chemo-sensitization, and circadian rhythms.Form:Solid.

InformationGlumetinib (SCC244) Glumetinib (SCC244) is a potent and highly selective c-Met inhibitor with an IC50 of 0.42 ± 0.02 nmol/L. Glumetinib has greater than 2,400-fold selectivity for c-Met over those 312 kinases evaluated, including the

Hepatocyte Growth Factor (HGF) is a multifunctional, heparin-binding factor that stimulates the proliferation of liver cells. The cellular effects of HGF are mediated by its receptor, c-Met, that leads to significant activation of ERK, Src/FAK,

GSK360A is an active HIF-PHD inhibitor. GSK360A has systemic and local effects by stabilizing HIF-1α signaling and can improve long-term ventricular function.

GSK360A is an active HIF-PHD inhibitor. GSK360A has systemic and local effects by stabilizing HIF-1α signaling and can improve long-term ventricular function.