Metformin/pioglitazone

Selective, noncompetitive inhibitor of the MAPK pathway prevents the activation of MAPKK1 by Raf or MEK kinase with an IC50 value of 2-7 &microM

Biochem/physiol Actions PD-161570 is an inhibitor of human FGF-1 receptor tyrosine kinase. Features and Benefits This compound is a featured product for Kinase Phosphatase Biology research.

Biochem/physiol Actions PD-161570 is an inhibitor of human FGF-1 receptor tyrosine kinase. Features and Benefits This compound is a featured product for Kinase Phosphatase Biology research.

PDGFs are disulfide-linked dimers consisting of two 12.0-13.

PDGF-BB, human: Platelet-derived growth factor (PDGF) presenting in serum but absent from plasma was first discovered in animal study by Lynch and co-workers in the late 1980s. It is a disulfide-linked dimer consisting of two peptides-chain A and

PDGF-BB, human: Platelet-derived growth factor (PDGF) presenting in serum but absent from plasma was first discovered in animal study by Lynch and co-workers in the late 1980s. It is a disulfide-linked dimer consisting of two peptides-chain A and

Platelet-Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle, connective tissue, bone and cartilage cells, and some blood cells. The PDGF is involved in a number of biological

Platelet-Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle, connective tissue, bone and cartilage cells, and some blood cells. The PDGF is involved in a number of biological

A CPT1 and CPT2 inhibitor that inhibits rat heart and liver CPT1 (IC₅₀ = 77 and 148 &microM, respectively), and rat heart CPT2 (IC₅₀ = 79 &microM) inhibits mTORC1 signaling and induces autophagy in MCF-7 cells at low

A selective inhibitor of casein kinase 1&epsilon (CK1&epsilon IC₅₀ = 32 nM) with greater than 20-fold selectivity over CK1&delta blocks CK1&epsilon-mediated PER3 nuclear localization and PER2 degradation, both of which are proteins

A phorbol ester that is commonly used to activate certain types of protein PKC and, indirectly, certain MAP kinase pathways prolonged treatment with PMA produces various effects, ranging from tumorigenesis to hematopoietic differentiation.

A phorbol ester that is commonly used to activate certain types of protein PKC and, indirectly, certain MAP kinase pathways prolonged treatment with PMA produces various effects, ranging from tumorigenesis to hematopoietic differentiation.