Metformin/rosiglitazone

Biochem/physiol Actions SGC-SMARCA-BRDVIII is a potent, SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomain (BRD) inhibitor that effectively blocks adipocyte differentiation in 3T3-L1 murine fibroblast cultures (1 &#956:M) by preventing the

Antigen: synthetic peptides corresponding to amino acids 85-99 and amino acids 372-388 of human SMAD6 Cross Reactivity: (+) Human, new world monkey, mouse, rat, and ovine SMAD6 predicted to react with horse SMAD6 Application(s): IHC, WB SMAD6 is an

Biochem/physiol Actions SR9238 is liver selective LXR inverse agonist with high potency for both LXR&#945: and LXR&#946: with an IC 50 of 214 nM for LXR&#945: and 43 nM for LXR&#946:. Metabolic syndrome is often accompanied by liver problems,

Biochem/physiol Actions SR9238 is liver selective LXR inverse agonist with high potency for both LXR&#945: and LXR&#946: with an IC 50 of 214 nM for LXR&#945: and 43 nM for LXR&#946:. Metabolic syndrome is often accompanied by liver problems,

Application STA-21 has been used as a signal transducer and activator of transcription 3 (STAT3) inhibitor to study its effects on glioblastoma and primary glioblastoma cells. It has also been used as a STAT3 dimerization inhibitor to study its

Application STA-21 has been used as a signal transducer and activator of transcription 3 (STAT3) inhibitor to study its effects on glioblastoma and primary glioblastoma cells. It has also been used as a STAT3 dimerization inhibitor to study its

Biochem/physiol Actions STM2457 is a potent and highly selective SAM-binding site METTL3 (MT-A70) m6A methyltransferase inhibitor (IC50 = 16.9 nM, Kd = 1.

Suberosin, isolated from Plumbago zeylanica, exhibits anti-inflammatory and anticoagulant activity. Suberosin suppresses PHA-induced PBMC proliferation and arrested cell cycle progression from the G1 transition to the S phase through the modulation

Suberosin, isolated from Plumbago zeylanica, exhibits anti-inflammatory and anticoagulant activity. Suberosin suppresses PHA-induced PBMC proliferation and arrested cell cycle progression from the G1 transition to the S phase through the modulation

General description O.D.

An inhibitor of Dkk1 that activates the Wnt signaling pathway, stimulating &beta-catenin/TCF-dependent transcription with an EC₅₀ value of 0.63 &microM has good pharmacokinetic properties and increases trabecular bone formation in

An inhibitor of Dkk1 that activates the Wnt signaling pathway, stimulating &beta-catenin/TCF-dependent transcription with an EC₅₀ value of 0.63 &microM has good pharmacokinetic properties and increases trabecular bone formation in