Netoglitazone

A PGE2 metabolite found in the semen of primates, including man potent smooth muscle relaxant and a selective agonist for the EP2 receptor (EC₅₀ = 200 nM for relaxing cat tracheal rings).

20-ethyl PGE2 is an analog of PGE2 in which the &omega-chain has been extended by the addition of two methylene carbon atoms. The only well studied prostaglandin analog with this structural feature is unoprostone, an F-series prostaglandin that is

20-ethyl PGE2 is an analog of PGE2 in which the &omega-chain has been extended by the addition of two methylene carbon atoms. The only well studied prostaglandin analog with this structural feature is unoprostone, an F-series prostaglandin that is

20-ethyl PGE2 is an analog of PGE2 in which the &omega-chain has been extended by the addition of two methylene carbon atoms. The only well studied prostaglandin analog with this structural feature is unoprostone, an F-series prostaglandin that is

Information3PO 3PO (3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one) is a small-molecule inhibitor of PFKFB3 with an IC50 of 22.9 μM for recombinant human PFKFB3 protein and does not inhibit PFK-1 activity. It suppresses glucose uptake, and decreases

Information3PO 3PO (3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one) is a small-molecule inhibitor of PFKFB3 with an IC50 of 22.9 μM for recombinant human PFKFB3 protein and does not inhibit PFK-1 activity. It suppresses glucose uptake, and decreases

Fluprostenol is a well-studied, potent analog of PGF2&alpha and acts primarily through the FP receptor. Oxidation at C-9 of fluprostenol yields 9-keto fluprostenol.

PGD2 is one of the five primary enzymatic prostaglandins derived directly from PGH2. PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and basophils by a second,

PGD2 is one of the five primary enzymatic prostaglandins derived directly from PGH2. PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and basophils by a second,

PGD2 is one of the five primary enzymatic prostaglandins derived directly from PGH2. PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and basophils by a second,

Biochem/physiol Actions ADH-1 is an N-cadherin (CD325: NCAD) antagonist that selectively inhibits NCAD-dependent neurite outgrowth (IC50 = 323 &#956:M: PN1-2 rat cerebral neurons on monolayer of chick NCAD-expressing 3T3), while exhibiting no

Biochem/physiol Actions ADH-1 is an N-cadherin (CD325: NCAD) antagonist that selectively inhibits NCAD-dependent neurite outgrowth (IC50 = 323 &#956:M: PN1-2 rat cerebral neurons on monolayer of chick NCAD-expressing 3T3), while exhibiting no