Netoglitazone

Application Potent FP prostanoid receptor agonist used in animal models for glaucoma.

A PGE2 metabolite found in the semen of primates, including man potent smooth muscle relaxant and a selective agonist for the EP2 receptor (EC₅₀ = 200 nM for relaxing cat tracheal rings).

A PGE2 metabolite found in the semen of primates, including man potent smooth muscle relaxant and a selective agonist for the EP2 receptor (EC₅₀ = 200 nM for relaxing cat tracheal rings).

20-ethyl PGE2 is an analog of PGE2 in which the &omega-chain has been extended by the addition of two methylene carbon atoms. The only well studied prostaglandin analog with this structural feature is unoprostone, an F-series prostaglandin that is

20-ethyl PGE2 is an analog of PGE2 in which the &omega-chain has been extended by the addition of two methylene carbon atoms. The only well studied prostaglandin analog with this structural feature is unoprostone, an F-series prostaglandin that is

20-ethyl PGE2 is an analog of PGE2 in which the &omega-chain has been extended by the addition of two methylene carbon atoms. The only well studied prostaglandin analog with this structural feature is unoprostone, an F-series prostaglandin that is

Information3PO 3PO (3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one) is a small-molecule inhibitor of PFKFB3 with an IC50 of 22.9 μM for recombinant human PFKFB3 protein and does not inhibit PFK-1 activity. It suppresses glucose uptake, and decreases

Information3PO 3PO (3-(3-pyridinyl)-1-(4-pyridinyl)-2-propen-1-one) is a small-molecule inhibitor of PFKFB3 with an IC50 of 22.9 μM for recombinant human PFKFB3 protein and does not inhibit PFK-1 activity. It suppresses glucose uptake, and decreases

9-deoxy-9-methylene Prostaglandin E|2|is a stable, isosteric analog of PGE|2|that retains the biological profile of PGE|2|with few side effects. In the rat 9-deoxy-9-methylene PGE|2|is equipotent to PGE|2|in decreasing blood pressure and It also

9-deoxy-9-methylene Prostaglandin E|2|is a stable, isosteric analog of PGE|2|that retains the biological profile of PGE|2|with few side effects. In the rat 9-deoxy-9-methylene PGE|2|is equipotent to PGE|2|in decreasing blood pressure and It also

Fluprostenol is a well-studied, potent analog of PGF2&alpha and acts primarily through the FP receptor. Oxidation at C-9 of fluprostenol yields 9-keto fluprostenol.

PGD2 is one of the five primary enzymatic prostaglandins derived directly from PGH2. PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and basophils by a second,