Netoglitazone

BMT-145027 is an mGluR5 positive allosteric modulator without inherent agonist activity, exhibits an EC 50 of 47 nM.In VitroBMT-145027 is a compound with high MsLM stability (85% remaining), acceptable potency (EC 50 =47 nM), and a modest decrease

BPIQ-I is an extremely potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) (IC|50|=25 pM).

Bufalin is a C-24 steroid with an α-pyrone ring positioned at C-17. It is present in the venom glands and skin of toad, Venenum Bufonis.Bufalin is a cardiotonic steroid[5] and is digoxin-like component of Chan Su.Bufalin has been used:• to test its

A structural analog of PGE2, is a selective agonist for the EP2 receptor subtype. EP2 receptors are expressed on human neutrophils and on respiratory, vascular, and uterine smooth muscle.1,2 This compound binds with about 1/10 the affinity of PGE2

A structural analog of PGE2, is a selective agonist for the EP2 receptor subtype. EP2 receptors are expressed on human neutrophils and on respiratory, vascular, and uterine smooth muscle.1,2 This compound binds with about 1/10 the affinity of PGE2

InformationAZD9833 is an orally available and selectiveestrogen receptor (ER)antagonist with antineoplastic activity.TargetsERIn vitroAZD9833 is demonstrated to be a highly potent selective estrogen receptor degraders (SERD) that shows a

InformationAZD9833 is an orally available and selectiveestrogen receptor (ER)antagonist with antineoplastic activity.TargetsERIn vitroAZD9833 is demonstrated to be a highly potent selective estrogen receptor degraders (SERD) that shows a

InformationAZD9833 is an orally available and selectiveestrogen receptor (ER)antagonist with antineoplastic activity.TargetsERIn vitroAZD9833 is demonstrated to be a highly potent selective estrogen receptor degraders (SERD) that shows a

InformationAZD9833 is an orally available and selectiveestrogen receptor (ER)antagonist with antineoplastic activity.TargetsERIn vitroAZD9833 is demonstrated to be a highly potent selective estrogen receptor degraders (SERD) that shows a

InformationCCG215022 CCG215022 serves as a pan- G protein-coupled receptor kinases (GRKs) inhibitor with IC50 of 3.9 μM, 0.15 μM, 0.38 μM for GRK1 , GRK2 , GRK5 , respectively.TargetsGRK2 (Cell-free assay): GRK5 (Cell-free assay): GRK1 (Cell-free

InformationCCG215022 CCG215022 serves as a pan- G protein-coupled receptor kinases (GRKs) inhibitor with IC50 of 3.9 μM, 0.15 μM, 0.38 μM for GRK1 , GRK2 , GRK5 , respectively.TargetsGRK2 (Cell-free assay): GRK5 (Cell-free assay): GRK1 (Cell-free

Human SSTR4 encoding SST4 Somatostatin is a 14 or 28 amino acid regulatory peptide that inhibits hormone secretion from the pituitary, pancreas, and other endocrine sites. A family of 6 GPCRs, sst1, sst2A, sst2B, sst3, sst4 and sst5, mediate the