Netoglitazone

Biochem/physiol Actions Iperoxo forms an important building block for the class of G protein-coupled receptors modulators. Iperoxo specifically binds to the orthosteric site of the muscarinic acetylcholine receptor.

Iperoxo is a potent superagonist of muscarinic acetylcholine receptor (mAChR). [ 3 H]Iperoxo can be used for direct probing activation-related conformational transitions of muscarinic receptors.

InformationIpragliflozin L-Proline is an orally active and selective inhibitor ofSGLT2with IC50 of 7.38 nM, 6.73 nM and 5.64 nM for human SGLT2, rat SGLT2 and mouse SGLT2, respectively.Targetsmouse SGLT2 (Cell-free assay): rat SGLT2 (Cell-free

InformationIpragliflozin L-Proline is an orally active and selective inhibitor ofSGLT2with IC50 of 7.38 nM, 6.73 nM and 5.64 nM for human SGLT2, rat SGLT2 and mouse SGLT2, respectively.Targetsmouse SGLT2 (Cell-free assay): rat SGLT2 (Cell-free

InformationIpragliflozin L-Proline is an orally active and selective inhibitor ofSGLT2with IC50 of 7.38 nM, 6.73 nM and 5.64 nM for human SGLT2, rat SGLT2 and mouse SGLT2, respectively.Targetsmouse SGLT2 (Cell-free assay): rat SGLT2 (Cell-free

InformationIpragliflozin L-Proline is an orally active and selective inhibitor ofSGLT2with IC50 of 7.38 nM, 6.73 nM and 5.64 nM for human SGLT2, rat SGLT2 and mouse SGLT2, respectively.Targetsmouse SGLT2 (Cell-free assay): rat SGLT2 (Cell-free

InformationIpragliflozin L-Proline is an orally active and selective inhibitor ofSGLT2with IC50 of 7.38 nM, 6.73 nM and 5.64 nM for human SGLT2, rat SGLT2 and mouse SGLT2, respectively.Targetsmouse SGLT2 (Cell-free assay): rat SGLT2 (Cell-free

InformationIpragliflozin L-Proline is an orally active and selective inhibitor ofSGLT2with IC50 of 7.38 nM, 6.73 nM and 5.64 nM for human SGLT2, rat SGLT2 and mouse SGLT2, respectively.Targetsmouse SGLT2 (Cell-free assay): rat SGLT2 (Cell-free

InformationIpragliflozin L-Proline is an orally active and selective inhibitor ofSGLT2with IC50 of 7.38 nM, 6.73 nM and 5.64 nM for human SGLT2, rat SGLT2 and mouse SGLT2, respectively.Targetsmouse SGLT2 (Cell-free assay): rat SGLT2 (Cell-free

A less potent IWP-2 derivative that has been used to determine which structural features of IWP-2 are essential for impairing Wnt/ &beta-catenin pathway activity.

A less potent IWP-2 derivative that has been used to determine which structural features of IWP-2 are essential for impairing Wnt/ &beta-catenin pathway activity.

A less potent IWP-2 derivative that has been used to determine which structural features of IWP-2 are essential for impairing Wnt/ &beta-catenin pathway activity.