Netoglitazone

MSDC 0160 (Mitoglitazone) is a mitochondrial target of thiazolidinediones (mTOT)-modulating insulin sensitizer and a modulator of mitochondrial pyruvate carrier (MPC). MSDC 0160 is a thiazolidinedione (TZD) with antidiabetic and neuroprotective

MSDC 0160 (Mitoglitazone) is a mitochondrial target of thiazolidinediones (mTOT)-modulating insulin sensitizer and a modulator of mitochondrial pyruvate carrier (MPC). MSDC 0160 is a thiazolidinedione (TZD) with antidiabetic and neuroprotective

MSDC 0160 (Mitoglitazone) is a mitochondrial target of thiazolidinediones (mTOT)-modulating insulin sensitizer and a modulator of mitochondrial pyruvate carrier (MPC). MSDC 0160 is a thiazolidinedione (TZD) with antidiabetic and neuroprotective

MSDC 0160 (Mitoglitazone) is a mitochondrial target of thiazolidinediones (mTOT)-modulating insulin sensitizer and a modulator of mitochondrial pyruvate carrier (MPC). MSDC 0160 is a thiazolidinedione (TZD) with antidiabetic and neuroprotective

MSDC 0160 (Mitoglitazone) is a mitochondrial target of thiazolidinediones (mTOT)-modulating insulin sensitizer and a modulator of mitochondrial pyruvate carrier (MPC). MSDC 0160 is a thiazolidinedione (TZD) with antidiabetic and neuroprotective

Biochem/physiol Actions MK-0524 is a potent and selective prostaglandin D2 (PGD2) receptor PTGDR (DP1) antagonist with inverse agonist activity (Ki = 570 pM/DP1, 2.95 nM/TP, 745 nM/DP2, &gt:890 nM for EP1/2/3/4, FP and IP).

Biochem/physiol Actions MK-0524 is a potent and selective prostaglandin D2 (PGD2) receptor PTGDR (DP1) antagonist with inverse agonist activity (Ki = 570 pM/DP1, 2.95 nM/TP, 745 nM/DP2, &gt:890 nM for EP1/2/3/4, FP and IP).

An inverse agonist of LRH-1 (IC₅₀ = 3.7 &microM) with maximum efficacy of 64% repression inactive at the related SF1 transcriptional activator alters the expression of haptoglobin, SAA1, and SAA4, induces the death of ER negative

An inverse agonist of LRH-1 (IC₅₀ = 3.7 &microM) with maximum efficacy of 64% repression inactive at the related SF1 transcriptional activator alters the expression of haptoglobin, SAA1, and SAA4, induces the death of ER negative

An inverse agonist of LRH-1 (IC₅₀ = 3.7 &microM) with maximum efficacy of 64% repression inactive at the related SF1 transcriptional activator alters the expression of haptoglobin, SAA1, and SAA4, induces the death of ER negative

An inverse agonist of LRH-1 (IC₅₀ = 3.7 &microM) with maximum efficacy of 64% repression inactive at the related SF1 transcriptional activator alters the expression of haptoglobin, SAA1, and SAA4, induces the death of ER negative

General description The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent