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Add to Cart The item has been added19142-500SB 239063-500 g
Price: $121.87List Price: $135.41A selective p38 MAP kinase inhibitor (IC<sub>50</sub> = 44 nM for p38&alpha) that has been shown to reduce inflammatory cytokine production and is neuroprotective following oral administration in vivo. -
Add to Cart The item has been added16281-1SB-525334-1 mg
Price: $108.73List Price: $120.82A potent inhibitor of the TGF-&beta receptor 1 (TGF-&beta R1, ALK5) kinase (IC<sub>50</sub> = 14.36 nM) blocks TGF-&beta1-induced phosphorylation and nuclear translocation of SMAD2/3 as well as TGF-&beta1-directed gene expression effective in -
Add to Cart The item has been added16281-10SB-525334-10 mg
Price: $317.34List Price: $352.60A potent inhibitor of the TGF-&beta receptor 1 (TGF-&beta R1, ALK5) kinase (IC<sub>50</sub> = 14.36 nM) blocks TGF-&beta1-induced phosphorylation and nuclear translocation of SMAD2/3 as well as TGF-&beta1-directed gene expression effective in -
Add to Cart The item has been added16281-5SB-525334-5 mg
Price: $211.92List Price: $235.46A potent inhibitor of the TGF-&beta receptor 1 (TGF-&beta R1, ALK5) kinase (IC<sub>50</sub> = 14.36 nM) blocks TGF-&beta1-induced phosphorylation and nuclear translocation of SMAD2/3 as well as TGF-&beta1-directed gene expression effective in -
Add to Cart The item has been added16281-50SB-525334-50 mg
Price: $1,280.01List Price: $1,422.24A potent inhibitor of the TGF-&beta receptor 1 (TGF-&beta R1, ALK5) kinase (IC<sub>50</sub> = 14.36 nM) blocks TGF-&beta1-induced phosphorylation and nuclear translocation of SMAD2/3 as well as TGF-&beta1-directed gene expression effective in -
Add to Cart The item has been addedS408658-1mlSB431542 (C007B-272085)
Price: $259.17List Price: $287.97InformationSB431542 is a potent and selective inhibitor ofALK5withIC50of 94 nM in a cell-free assay, 100-fold more selective for ALK5 than p38 MAPK and other kinases.In vitroSB 431542 inhibits the activin type I receptor ALK4 and the nodal type I -
Add to Cart The item has been added16619-5SD 208-5 mg
Price: $313.55List Price: $348.39A potent inhibitor of TGF-&betaRI kinase (EC<sub>50</sub> = 48 nM) that has minimal or no effect at a variety of other kinases blocks both autocrine and paracrine TGF-&beta signaling in glioma cells is orally bioavailable and prevents -
Add to Cart The item has been addedS288249-100mgSGC AAK1 1 (C007B-269075)
Price: $1,143.12List Price: $1,270.14AAK1 and BMP2K inhibitor: activates Wnt signaling. -
Add to Cart The item has been addedS288249-25mgSGC AAK1 1 (C007B-269076)
Price: $383.75List Price: $426.39AAK1 and BMP2K inhibitor: activates Wnt signaling. -
Add to Cart The item has been addedS288249-5mgSGC AAK1 1 (C007B-269077)
Price: $136.56List Price: $151.73AAK1 and BMP2K inhibitor: activates Wnt signaling. -
Add to Cart The item has been addedS413169-100mgSildenafil Mesylate (C007B-272405)
Price: $298.83List Price: $332.03InformationSildenafil Mesylate is a mesylate form of Sildenafil, an inhibitor ofPhosphodiesterase 5.TargetsPDE5In vivoChronic sildenafil treatment increases the detumescence phase in young and aged rats (p<:0.05), although aged rats show a greater -
Add to Cart The item has been addedS413169-1gSildenafil Mesylate (C007B-272406)
Price: $668.80List Price: $743.11InformationSildenafil Mesylate is a mesylate form of Sildenafil, an inhibitor ofPhosphodiesterase 5.TargetsPDE5In vivoChronic sildenafil treatment increases the detumescence phase in young and aged rats (p<:0.05), although aged rats show a greater
