Netoglitazone

SNT-207707 is a selective, potent and orally active melanocortin MC-4 receptor antagonist with an IC 50 of 8 nM (binding) and 5 nM (function) on the MC-4 receptor.In VitroSNT-207707 binds to the MC-4 receptor with an affinity of 8 nM and shows a

SNT-207707 is a selective, potent and orally active melanocortin MC-4 receptor antagonist with an IC 50 of 8 nM (binding) and 5 nM (function) on the MC-4 receptor.In VitroSNT-207707 binds to the MC-4 receptor with an affinity of 8 nM and shows a

SNT-207707 is a selective, potent and orally active melanocortin MC-4 receptor antagonist with an IC 50 of 8 nM (binding) and 5 nM (function) on the MC-4 receptor.In VitroSNT-207707 binds to the MC-4 receptor with an affinity of 8 nM and shows a

InformationSotorasib (AMG510) Sotorasib (AMG510) is a potent KRAS G12C covalent inhibitor with potential antineoplastic activity. This AMG510 is a chiral compound.In vitroAMG 510 inhibits SOS1-catalyzed nucleotide exchange of recombinant mutant KRAS

Application SR-18292 Maleate has been used as a peroxisome proliferator-activated receptor &#947: coactivator 1 &#945: (PGC1&#945:) inhibitor to study the protective effects of pioglitazone on demyelinated axons. Biochem/physiol Actions

Application SR-18292 Maleate has been used as a peroxisome proliferator-activated receptor &#947: coactivator 1 &#945: (PGC1&#945:) inhibitor to study the protective effects of pioglitazone on demyelinated axons. Biochem/physiol Actions

SSR504734 is an orally active, selective and reversible inhibitor of human, rat, and mouse GlyT1 ( IC 50 =18, 15, and 38 nM, respectively). SSR504734 shows anti-schizophrenia, anti-anxiety and anti-depression activitiesIn VitroSSR504734 (15 nM-86

SSR504734 is an orally active, selective and reversible inhibitor of human, rat, and mouse GlyT1 ( IC 50 =18, 15, and 38 nM, respectively). SSR504734 shows anti-schizophrenia, anti-anxiety and anti-depression activitiesIn VitroSSR504734 (15 nM-86

Product Describtion:SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGFRβ, respectively.

Biochem/physiol Actions SUN11602 is an orally active basic fibroblast growth factor (bFGF, FGF2) mimetic that protects against glutamate toxicity in primary rat cerebrocortical neuron (0.1-1 &#956:M SUN11602: 150 &#956:M glutamate) and murine

Biochem/physiol Actions SUN11602 is an orally active basic fibroblast growth factor (bFGF, FGF2) mimetic that protects against glutamate toxicity in primary rat cerebrocortical neuron (0.1-1 &#956:M SUN11602: 150 &#956:M glutamate) and murine

A cell-permeable triaminotriazine that selectively inhibits the autoubiquitnation of the E3 ubiquitin ligase synoviolin (SYVN1, IC 50 = 35 &#181M), without affecting other E3 ubiquitin ligases. Abolished the SYVN-mediated negative regulation of