Pioglitazone hydrochloride

CCG258208 (GRK2-IN-1) hydrochloride is a potent and selective GRK2 ( G protein-coupled receptor kinase 2 ) inhibitor ( IC 50 =30 nM) while maintaining 230-fold selectivity over GRK5 ( IC 50 =7.09 μM) and more than 2500-fold selectivity over GRK1 (

CCG258208 (GRK2-IN-1) hydrochloride is a potent and selective GRK2 ( G protein-coupled receptor kinase 2 ) inhibitor ( IC 50 =30 nM) while maintaining 230-fold selectivity over GRK5 ( IC 50 =7.09 μM) and more than 2500-fold selectivity over GRK1 (

CCT367766 formic is a potent and the third generation heterobifunctional and Cereblon -based pirin targeting protein degradation probe (PDP, or PROTAC), depletes pirin protein expression at low concentration. CCT367766 formic exhibits a moderate

CCT367766 formic is a potent and the third generation heterobifunctional and Cereblon -based pirin targeting protein degradation probe (PDP, or PROTAC), depletes pirin protein expression at low concentration. CCT367766 formic exhibits a moderate

A potent, selective inhibitor of the kinase activity of fibroblast growth factor receptors (FGFRs) 1, 2, and 3 (IC₅₀s = 9.3, 7.

The dihydroxy-leukotriene, leukotriene B4 (LTB4) is a member of the G protein-coupled receptor (GPCR) family, in a subfamily of GPCRs that includes receptors for chemokines and other chemotactic factors. Recently, a second, lower affinity receptor

cis-Clopidogrel-MP derivative- 13 C,d 3 is a 13 C and deuterium labele cis-Clopidogrel-MP derivative. cis-Clopidogrel-MP derivative is a 3’-methoxyacetophenone derivative of Clopidogrel active metabolite. Clopidogrel is a well-known and orally

Biochem/physiol Actions CMPD101 is an active site-targeting, potent and subtype-selective G protein-coupled receptor kinase GRK2 &amp: GRK3 inhibitor (human GRK2/3 IC 50 = 54/32 nM with 3 &#956:M ATP and tubulin dimer as substrate: bovine GRK2 IC

Biochem/physiol Actions CMPD101 is an active site-targeting, potent and subtype-selective G protein-coupled receptor kinase GRK2 &amp: GRK3 inhibitor (human GRK2/3 IC 50 = 54/32 nM with 3 &#956:M ATP and tubulin dimer as substrate: bovine GRK2 IC

Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is a potent, selective and ATP-competitive pan-class I PI3K inhibitor, with IC 50 s of 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα , PI3Kδ , PI3Kβ and PI3Kγ , respectively. Copanlisib

Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is a potent, selective and ATP-competitive pan-class I PI3K inhibitor, with IC 50 s of 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα , PI3Kδ , PI3Kβ and PI3Kγ , respectively. Copanlisib

Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is a potent, selective and ATP-competitive pan-class I PI3K inhibitor, with IC 50 s of 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα , PI3Kδ , PI3Kβ and PI3Kγ , respectively. Copanlisib