Pioglitazone hydrochloride

Potent PI 3-kinase inhibitor: also inhibits DNA-PK and mTOR.

A naturally-derived flavone with anti-inflammatory, anti-oxidative, and anti-tumor effects induces apoptosis in human cancer cells down-regulates certain genes responsible for cellular oxidative stress, and acts as a selective PPAR&alpha agonist

InformationFG-2216 FG-2216 is a potent, and orally active HIF prolyl 4-hydroxylase inhibitor with IC50 of 3.9 μM for PHD2 . Phase 2.TargetsPHD2 (Cell-free assay) 3.9 μMIn vitroFG-2216 shows the ability to stabilize HIF-α to stimulate EPO

General description Furosemide&nbsp:is a an ototoxic high-ceiling diuretic. Application Furosemide has been used: to investigate the influence of timing of dexamethasone administration on auditory hair cell survival in mice to study its

DescriptionFmoc-L-photo-proline is a diazirine-containing, Fmoc-protectedproline amino acid andmultifunctional probe building blocks. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular

MF: C24H22N2O6 MF: 434.45 CAS: 109074-94-4 Purity: 99% by HPLC

Synonyms: Fmoc-L-propargyl-Gly-OHFmoc-L-Pra-OH(S)-2-(Fmoc-amino)-4-pentynoic acid Purity Limit: &ge 99% (HPLC, Chiral purity) CAS No.: 198561-07-8 Molecular Formula: C20H17NO4 Molecular Weight: 335.

Fmoc-Lys(iPr, Boc)-OH is used for incorporation of N -d-isopropyl-lysine (Lys(iPr)) during Fmoc SPPS. Lys(iPr) has been utilized in the GnRH antagonist Degarelix and the LHRH antagonist Antide.

Biochem/physiol Actions Aromatase inhibitor used as an anti-cancer agent against estrogen-dependent tumors.

Cell Line Origin Rat Dunning R-3327,prostate adenocarcinoma Cell Line Description Derived from a Dunning R-3327 rat with prostatic adenocarcinoma. G is one of a group of variants which developed by a single in vivo passage.

GDC-0927 (SRN-927) is a potent, non-steroidal, orally bioavailable, selective estrogen receptor antagonistIn VivoGDC-0927 is a novel, potent, non-steroidal, orally bioavailable, selective ER antagonist/ER degrader (SERD) that induces tumor

GDC-0927 (SRN-927) is a potent, non-steroidal, orally bioavailable, selective estrogen receptor antagonistIn VivoGDC-0927 is a novel, potent, non-steroidal, orally bioavailable, selective ER antagonist/ER degrader (SERD) that induces tumor