Pioglitazone hydrochloride

Application PHA 767491 hydrochloride has been used to study its effect on estrogen-induced DNA damage. It has also been used in western blot analysis and to study the S9.

Application Reagent used for Rhodium-catalyzed intramolecular amination Pd-catalyzed direct arylation Mizoroki-Heck and Suzuki-Miyaura coupling reactions catalyzed by palladium nanoparticles Palladium-catalyzed stereoselective Heck-type

An inactive analog of the PHGDH inhibitors NCT-502 and NCT-503.

An inactive analog of the PHGDH inhibitors NCT-502 and NCT-503.

Biochem/physiol Actions PHTPP is a selective estrogen receptor &#946: (ER&#946:) full antagonist with 36-fold selectivity for ER&#946: over ER&#945:. PHTPP has been used to distinguish the various activites of the two estrogen receptors.

Biochem/physiol Actions PHTPP is a selective estrogen receptor &#946: (ER&#946:) full antagonist with 36-fold selectivity for ER&#946: over ER&#945:. PHTPP has been used to distinguish the various activites of the two estrogen receptors.

Product descriptionPI-103 Hydrochloride is a dual PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α, p110β, p110δ, p110γ, mTORC1, and mTORC2. PI-103 Hydrochloride also inhibits DNA-PK with an IC50 of 2 nM.

Product descriptionPI-103 Hydrochloride is a dual PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110α, p110β, p110δ, p110γ, mTORC1, and mTORC2. PI-103 Hydrochloride also inhibits DNA-PK with an IC50 of 2 nM.

A cell-permeable triazinyl-phenyl-pyridinylurea compound that acts as a potent inhibitor against mTOR (IC 50 = 0.42 nM) and PI 3-K (IC 50 = 8, 24, 74, 77, 14, and 11 nM against isoform &#945, &#946, &#947, &#948, &#945 E545K mutant, and &#945

PI3K/mTOR Inhibitor-4 is an orally active pan-class I PI3K/mTOR inhibitor. PI3K/mTOR Inhibitor-4 has enzymatic inhibition activity for PI3Kα , PI3Kγ , PI3Kδ and mTOR with IC 50 values of 0.63 nM, 22 nM, 9.2 nM and 13.85 nM, respectively. PI3K/mTOR

PI3K/mTOR Inhibitor-4 is an orally active pan-class I PI3K/mTOR inhibitor. PI3K/mTOR Inhibitor-4 has enzymatic inhibition activity for PI3Kα , PI3Kγ , PI3Kδ and mTOR with IC 50 values of 0.63 nM, 22 nM, 9.2 nM and 13.85 nM, respectively. PI3K/mTOR

Application Pifithrin-&#945: has been used: to study the effect of specific p53 inhibitor on p53-upregulated modulator of apoptosis (PUMA) expression after transient global cerebral ischemia (tGCI) as p53 inhibitor to treat PA1 cells as a