Troglitazone

CP-547632 TFA is an orally active, ATP-competitive and potent VEGFR-2 and FGF kinases inhibitor with IC 50 s of 11 nM and 9 nM, respectively. CP-547632 TFA is selective for VEGFR2 and bFGF over EGFR , PDGFRβ , and related tyrosine kinases (TKs).

CP-547632 TFA is an orally active, ATP-competitive and potent VEGFR-2 and FGF kinases inhibitor with IC 50 s of 11 nM and 9 nM, respectively. CP-547632 TFA is selective for VEGFR2 and bFGF over EGFR , PDGFRβ , and related tyrosine kinases (TKs).

CP-547632 TFA is an orally active, ATP-competitive and potent VEGFR-2 and FGF kinases inhibitor with IC 50 s of 11 nM and 9 nM, respectively. CP-547632 TFA is selective for VEGFR2 and bFGF over EGFR , PDGFRβ , and related tyrosine kinases (TKs).

CP-547632 TFA is an orally active, ATP-competitive and potent VEGFR-2 and FGF kinases inhibitor with IC 50 s of 11 nM and 9 nM, respectively. CP-547632 TFA is selective for VEGFR2 and bFGF over EGFR , PDGFRβ , and related tyrosine kinases (TKs).

KDM4C (Cell-free assay): KDM4A (Cell-free assay) 29 nM: 42 nMIn vitroCP2 uniquely binds in the KDM4A substrate-binding pocket. It binds differently to, but competes with, histone substrates in the active site.

des-Gln14-Ghrelin (rat) TFA.

des-Gln14-Ghrelin (rat) TFA.

des-Gln14-Ghrelin (rat) TFA.

Biochem/physiol Actions Diquafosol (Up4U, INS365) is a selective purinergic receptor P2Y2 agonist (EC50 = 100 nM/P2Y2, 400 nM/P2Y4, 20 &#956:M/P2Y6, &gt:100 &#956:M/P2Y1 by calcium mobilization using respective 1321N P2Y subtype transfectants). In

DMM TRMS IP67

DVD-445 (Compound 7) is a potent peptidomimetic covalent thioredoxin reductase 1 (TrxR1) inhibitor with an IC 50 of 0.60 μM for rat TrxR1. DVD-445 has good anticancer applicationIn VitroDVD-445 (Compound 7) shows a cytotoxic effect in SH-SY5Y, U87,

A cell-permeable amidobenzanilide compound that disrupts Fz-Dvl (frizzled-dishevelled) interaction by targeting the PDZ domain ( K d = 10.6 &#181M) of Dvl, blocking Wnt3a-induced (10 ng/ml) transcription activity (~50% inhibition at 3 &#181M in