Immunomodulating drugs

General description Anti-CSPN3 Antibody detects endogenous levels of total CSPN3 protein. Immunogen The antiserum was produced against synthesized peptide derived from human Caspase 3.

General description Anti-CSPN7 (p20, Cleaved-Asp 198 ) Antibody detects endogenous levels of fragment of activated CSPN7 (p20, Cleaved-Asp 198 ) protein. Immunogen The antiserum was produced against synthesized peptide derived from human Caspase

Anti-CASP8 caspase 8, apoptosis-related cysteine peptidase,

CASP8AP2 codes for caspase 8 associated protein 2 and it may be implicated in apoptosis. This gene has been studied as a prognostic biomarker in pediatric acute lymphoblastic leukemia.

Anti-CASP8AP2 caspase 8 associated protein 2, 25ul UN 1687 6

CASP9 (Caspase-9) gene encodes a protein belonging to the cysteine-aspartic acid protease (caspase) family. It consists of two domains.

General description This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.

Three distinct signaling pathways lead to apoptosis. The death receptor and mitochondrion pathways are the two mains, which involve respectively caspase-8 and caspase-9.

Specificity MAB3507 antibody recognizes a reactive epitope that lies in the P19 subunit of human Caspase-2 (ICH-1, Nedd-2). Immunogen Raised against the P19 subunit of recombinant human Caspase-2 protein.

Caspase 3 is a cytosolic protein present as a 32 kDa proenzyme in cells. It is activated by proteolytic cleavage into the 20 kDa (p20) and 11 kDa (p11) active subunits when cells undergo apoptosis.

Caspase-3 (CASP3) belongs to the class of cysteine proteases. CASP3&nbspis an executioner caspase, which is cleaved and activated with the help of caspase-8 and caspase-9 initiator caspases.

Caspase-3 (CASP3) belongs to the class of cysteine proteases. CASP3&nbspis an executioner caspase, which is cleaved and activated with the help of caspase-8 and caspase-9 initiator caspases.