Immunomodulating drugs

Anti-CASP8AP2 caspase 8 associated protein 2, 25ul UN 1687 6

CASP9 (Caspase-9) gene encodes a protein belonging to the cysteine-aspartic acid protease (caspase) family. It consists of two domains.

General description This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.

Three distinct signaling pathways lead to apoptosis. The death receptor and mitochondrion pathways are the two mains, which involve respectively caspase-8 and caspase-9.

Specificity MAB3507 antibody recognizes a reactive epitope that lies in the P19 subunit of human Caspase-2 (ICH-1, Nedd-2). Immunogen Raised against the P19 subunit of recombinant human Caspase-2 protein.

Caspase 3 is a cytosolic protein present as a 32 kDa proenzyme in cells. It is activated by proteolytic cleavage into the 20 kDa (p20) and 11 kDa (p11) active subunits when cells undergo apoptosis.

Caspase-3 (CASP3) belongs to the class of cysteine proteases. CASP3&nbspis an executioner caspase, which is cleaved and activated with the help of caspase-8 and caspase-9 initiator caspases.

Caspase-3 (CASP3) belongs to the class of cysteine proteases. CASP3&nbspis an executioner caspase, which is cleaved and activated with the help of caspase-8 and caspase-9 initiator caspases.

Caspase-3 (CPP32, Apopain) is the most extensively studied apoptotic protein. Caspase-3 is synthesized as an inactive proenzyme (32 kDa) that is processed in cells undergoing apoptosis by self-proteolysis and/or cleavage by another upstream

Specificity Recognizes a protein of 32 kDa, identified as the Caspase-3 protein. Highly specific to Caspase-3 and shows no cross-reaction with other caspase family members.

General description This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.

General description This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.